The 3-nitrooxypropanol, or 3NOP supplement, blocks an enzyme necessary to catalyze the last step of methane creation by the microbes in the rumen.

The cows that consumed a feed regimen supplemented by the novel methane inhibitor compound over the course of the 12-week study gained 80% more body weight than cows in a control group. Hristov said, "The spared methane energy was used partially for tissue synthesis, which led to a greater body weight gain by the inhibitor-treated cows."
The findings showed that the feed intake, fiber digestibility and milk production by cows that consumed the supplement did not decrease. Hristov said, "The 3NOP compound, developed by DSM Nutritional Products, a Dutch company that is one of the world's leading suppliers of feed additives, seems to be safe and effective. If approved by the US Food and Drug Administration (FDA) and adopted by the agricultural industry, this methane inhibitor could have a significant impact on greenhouse gas emissions from the livestock sector."
The findings were published in Proceedings of the National Academy of Sciences.
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