Prostaglandins Other Lipid Mediat.
The COX-2 inhibitor NS398 selectively sensitizes hypoxic HeLa cells to ionising radiation by mechanisms both dependent and independent of COX-2.
Anoopkumar-Dukie S, Conere T, Houston A, King L, Christie D, McDermott C, Allshire A
It is widely accepted that the hypoxic nature of solid tumors contribute to their resistance to radiation therapy. There is increasing evidence that c ...
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Source: PubMed
BMJ
Selective COX-2 inhibitors are safe and effective.
Beales ILP
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Source: PubMed
PLoS ONE
A comparative study of the efficacy of NAXOZOL compared to celecoxib in patients with osteoarthritis.
Park MS, Kang CN, Lee WS, Kim HJ, Lee S, Kim JH, Shin SJ, Moon SH
Selective cyclooxygenase-2 inhibitors (celecoxib) can minimize the gastrointestinal complications related to non-steroidal anti-inflammatory drug (NSA ...
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Source: PubMed
Biomolecules
Discrimination of Naturally-Occurring 2-Arylbenzofurans as Cyclooxygenase-2 Inhibitors: Insights into the Binding Mode and Enzymatic Inhibitory Activity.
Coy-Barrera E
2-arylbenzofuran-containing compounds are chemical entities that can be naturally produced by several organisms. A wide-range of activities is describ ...
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Source: PubMed
Molecules
Synthesis of Novel Benzodifuranyl; 1,3,5-Triazines; 1,3,5-Oxadiazepines; and Thiazolopyrimidines Derived from Visnaginone and Khellinone as Anti-Inflammatory and Analgesic Agents.
Abu-Hashem AA, Al-Hussain SA, Zaki MEA
Novel (4-methoxy or 4,8-dimethoxy)-3-methyl-N-(6-oxo-2-thioxo-1,2,3, 6-tetrahydro- pyrimidin-4-yl) benzo [1,2-b: 5, 4-b'] difuran-2-carboxamide (5a-b) ...
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Source: PubMed
