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Side effect(s) of Ocrelizumab


Review the side-effects of Ocrelizumab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
• Common: Injection site reactions (pain or redness), respiratory infections
• Gastrointestinal: Bloating, diarrhea, loss of appetite
• Central nervous system: Irritability, lack of interest, difficulty in sleeping or concentrating, depression
• Musculoskeletal: Back pain, pain in the extremities
• Respiratory: Sneezing, sore throat, cough, difficulty in breathing
• Others: Herpes virus related infections, reduced neutrophil counts, skin related infections

Other Precautions :

• The infusion rate can be reduced to half for at least 30 minutes in case of mild to moderate infusion reactions.
• The prepared solution before infusing should be brought to room temperature. The diluted solution should be stored either in the refrigerator at 2°C to 8°C for 24 hours or for 8 hours at room temperature including the infusion time.

Drug Name : Ocrelizumab

Ocrelizumab generic Ocrelizumab is prescribed for treating adult patients who suffer from either the remitting or relapsing form or primary progressive form of multiple sclerosis. It is a humanized anti-CD 20 monoclonal antibody which works by stopping some of the cells of the immune system from inducing damage. Multiple sclerosis is a condition in which the nerves do not work properly; the patients may feel numbness , lack of muscle coordination, and problems with vision, speech, and bladder control.


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