Read the side effects of Inotersen as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Nausea, vomiting, reduced appetite, dry mouth
Headache, fever, abnormal weakness
Abnormal heart rhythm, swelling of the hands and foot or ankles, reduction in blood pressure while standing suddenly from a sitting or lying position
Breathing difficulty, flu-like symptoms
Injection site reactions such as rashes, redness, pain, and swelling
Abnormal levels of hemoglobin, platelets, liver enzymes, bilirubin, creatinine, and glomerular filtration rate
Muscle pain, contusion or bruising, bacterial infections
Other Precautions :
Inotersen prefilled syringes should be removed from the refrigerator and kept outside to come to room temperature for a minimum of 30 minutes before injecting.
Do not drop in hot water or place in a microwave oven with the intention of warming the prefilled syringe.
Patients must be encouraged to actively get involved in the REMS (Risk Evaluation and Mitigation Strategy) program and should inform the doctor if any side effects occur.
Participating in all monitoring programs to detect the risk of bleeding disorders
or kidney damage is also advised.