Side effect(s) of Inotersen

Read the side effects of Inotersen as described in the medical literature. In case of any doubt consult your doctor or pharmacist.
Gastrointestinal: Nausea, vomiting, reduced appetite, dry mouth

Nervous system: Headache, fever, abnormal weakness

Cardiovascular: Abnormal heart rhythm, swelling of the hands and foot or ankles, reduction in blood pressure while standing suddenly from a sitting or lying position

Respiratory: Breathing difficulty, flu-like symptoms

Skin: Injection site reactions such as rashes, redness, pain, and swelling

Lab abnormalities: Abnormal levels of hemoglobin, platelets, liver enzymes, bilirubin, creatinine, and glomerular filtration rate

Others: Muscle pain, contusion or bruising, bacterial infections

Other Precautions : Inotersen prefilled syringes should be removed from the refrigerator and kept outside to come to room temperature for a minimum of 30 minutes before injecting.

Do not drop in hot water or place in a microwave oven with the intention of warming the prefilled syringe.

Patients must be encouraged to actively get involved in the REMS (Risk Evaluation and Mitigation Strategy) program and should inform the doctor if any side effects occur.

Participating in all monitoring programs to detect the risk of bleeding disorders or kidney damage is also advised.
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