Mitomycin - Indications, Dosage, Side Effects and Precautions


Information about Mitomycin

Generic Name : Mitomycin
Up-to-date prescription details regarding Mitomycin are provided here.

Pronunciation : mye toe mye' sin

Learn the correct pronunciation of the Mitomycin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Mitomycin

India :

International :


Why is Mitomycin Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for adenocarcinoma (cancer of the stomach or pancreas) either alone or with other medications.  It blocks cancer cell growth.

When should Mitomycin not be taken? (Contraindications)

Contraindicated in patients with bleeding disorder due to low platelet counts and hypersensitivity.

What is the dosage of Mitomycin?

IV- The recommended initial dose is 10 to 20 mg/m2, every 6 to 8 weeks.

How should Mitomycin be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Mitomycin?

• Caution should be exercised in patients with history of kidney, breathing, bone marrow problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

• It may reduce platelet counts, which lead to severe bleeding; avoid injury or bruising.

• Avoid contact with people who have infections.

• Avoid vaccination during the treatment period.

• Monitor complete blood cell count, and kidney function regularly while taking this medication.

What are the side effects of Mitomycin?

Severe effects - Bone marrow depression, heart failure, liver and kidney damage, abnormal decrease in platelet counts.
Gastrointestinal - Nausea, vomiting, anorexia, and mouth ulcer.
Skin - Hair loss, nail discoloration, rash and itching.
Respiratory - Lung infection/inflammation, cough and difficulty in breathing.
Miscellaneous - Fever, tingling, elevated liver enzyme, uneasiness and bladder fibrosis/contraction.

What are the other precautions for Mitomycin?

Avoid excess dosage.

What are the storage conditions for Mitomycin?

Normally handled and stored by healthcare providers.
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