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Vitamin B-6 - Toxicity

Medically Reviewed by The Medindia Medical Review Team on Feb 04, 2016


Toxicity

Pyridoxine toxicity is manifested at very high doses of the vitamin of the order of 500 to 1000mg/day or even higher.


This dosage may trigger sensory nerve damage which may cause pain and numbness of the extremities. Surprisingly, women who are consuming only about 50 mg/day of vitamin B-6 for PMS have reported neurological symptoms. Another disadvantage is that it can also decrease the effectiveness of Levodopa, a medication used to treat Parkinson's Disease.

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