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Leucovorin - Drug Information

Medically Checked by S. Hemamalini, B. Pharm


Generic Name : Leucovorin
Pronunciation : loo-koh-VOR-in

ICD Code : Y51.1 | Therapeutic Classification : Cholinergic Agents

Trade Name(s) :

India - Biovorin (5 ml), Cafonate, Cafonate Injection, Calcium Leucovorin, Calcium Leucovorin, Calcium Leucovorin (2ml), Calcium Leucovorin (5 ml), Calicium Leucovorin, Calicium Leucovorin (3 mg), Calicium Leucovorin (5 ml), Covorin, Covorin (15 mg), Covorin (2 ml), Covorin (5 ml), Dalisol, Dalisol Inj 50, Dalisol Inj., Fastovorin, Fastovorin (15 mg), Fastovorin (50 mg), Ferbon Korea, Ferbon -Korea (16 mg), Ferbon -Korea (2 ml), Leucovorin, Leucovorin (2 ml), Leucovorin (5 ml), Leucovorin Calcium, Leucovorin Calcium (2 ml), Lucal, Nyrin

More

International - Wellcovorin.



Other Name : Folinic acid, citrovorum factor, 5-formyl tetrahydrofolate.

Why is Leucovorin Prescribed? (Indications)

This medication is a folic acid analog, prescribed for reducing the toxic effects of methotrexate. It works by replacing folic acid in the body.

When should Leucovorin not to be taken? (Contraindications)

Contraindicated in patients with anemia (B12 deficiency) and hypersensitivity.

What is the dosage of Leucovorin?

IM/IV/PO- The recommended dose is 15 mg (10 mg/m2) every 6 hours.

How should Leucovorin be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein or muscle. It also comes as a tablet to take by mouth.

What are the warnings and precautions for Leucovorin?

* Caution needed for patients with history of blood problems, pleural effusion, during pregnancy and breastfeeding.

What are the side effects of Leucovorin?

Diarrhea, severe allergic reactions like rash, hives, itching, and difficulty in breathing or swallowing.

What are the other precautions for Leucovorin?

* Avoid excess dosage.

What are the storage conditions for Leucovorin?

Store in refrigerated conditions (2 to 8�C), protect from light and heat.

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