Choriogonadotropin Alfa - Drug Information
Generic Name : Choriogonadotropin Alfa
Pronunciation : KOR-ee-oh-goe-NAD-oh-TROE-pin AL-fa
ICD Code : E23.0 | Therapeutic Classification : Fertility Drug
Trade Name(s) :
India - Ovitrelle.International - Ovidrel, Novarel, Pregnyl.
Why is Choriogonadotropin Alfa Prescribed? (Indications)
This medication is used for treating anovulatory infertility due to hypothalamic pituitary desensitization, in vitro fertilization and other assisted reproductive procedures.When should Choriogonadotropin Alfa not to be taken? (Contraindications)
Contraindicated in patients with known hypersensitivity to human chorionic gonadotropin (hCG), primary ovarian failure, uncontrolled thyroid and adrenal dysfunction, abnormal uterine bleeding, fibroid uterine tumors, pregnant and breastfeeding women.What is the dosage of Choriogonadotropin Alfa?
Adult: Single 250-mcg dose when optimal stimulation of follicular growth is achieved.How should Choriogonadotropin Alfa be taken?
It comes as a solution for injection, subcutaneous 250 mcg 1 day after the last dose of follicle-stimulating agent.What are the warnings and precautions for Choriogonadotropin Alfa?
* Caution should be exercised in patients with history of asthma, epilepsy, migraine, cardiovascular disorders, kidney disorders, liver impairment.* Withhold this medication when there is an excessive ovarian response.
* Monitor carefully estradiol levels and ovarian response based on ultrasound prior to and during stimulation therapy.
* This medication increases the risk of multiple pregnancies.
What are the side effects of Choriogonadotropin Alfa?
Common - Irritability, swelling of the hands or legs, weight gain, breast pain, headaches, injection site problems, nausea ,ovarian hyperstimulation syndrome, stomach pain, tiredness, vomiting.Gastrointestinal - Severe pelvic pain, swelling.
Central nervous system - Depression.
Respiratory - Shortness of breath.
Genitourinary - Urinating less than normal, ovarian torsion, ectopic pregnancy.