Targeted Therapy for Inflammation of the Kidneys Identified
Inflammation inhibitor, protein kinase C-a, delivered directly to kidneys may reverse the course of destructive nephritis, a research team at the Medical College of Georgia at Augusta University finds.
Inflammation inhibitor, protein kinase C-a, delivered directly to kidneys may reverse the course of destructive nephritis, a research team at the Medical College of Georgia at Augusta University finds.
‘A smart drug delivery system that delivers the anti-inflammatory drug methylprednisolone can be used to reduce inflammation in damaged nervous tissues in spinal cord injuries and other neurological disorders. The delivery system can also be used to treat other diseases that involve inflammation.’
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The system protects nerve fibers (axons) that connect nerve cells in injured neural tissues as it uses extremely thin biomaterials. Read More..
Inflammation is a major factor when recovering from central nervous system injuries and diseases. Suppressing the immune system during treatment can lead to side effects and boost the risk of infection.
"A major goal is to suppress neuroinflammation and restore a healthy micro-environment at sites of neurological disorders," said senior author KiBum Lee.
Novel Imaging Technique for Joint Inflammation in Rheumatoid Arthritis
Novel positron emission tomography (PET) imaging method that more fully evaluates the extent of rheumatoid arthritis inflammation has been developed by a research team. The new method is designed to target translocator protein (TSPO) expression in the synovium.
Novel positron emission tomography (PET) imaging method that more fully evaluates the extent of rheumatoid arthritis inflammation has been developed by a research team. The new method is designed to target translocator protein (TSPO) expression in the synovium.
The drug delivery system consists of sugar polymers, ultrathin nanomaterials and neural proteins. The system releases an anti-inflammatory molecule called methylprednisolone. This molecule creates a favorable microenvironment to promote tissue repair and recovery after neurological injury.
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Chronic Inflammation a Risk for White Matter Disease in Older Adults
Increasing and persistent chronic inflammation in the decades spanning middle-to late-life is tied to white matter diseases in older adults. It has an adverse effect on important aspects of the brain's structure necessary for cognitive function.
Increasing and persistent chronic inflammation in the decades spanning middle-to late-life is tied to white matter diseases in older adults. It has an adverse effect on important aspects of the brain's structure necessary for cognitive function.
The team believes that the drug delivery system can be used to treat other diseases which involves inflammation such as cardiovascular disease, diabetes, osteoarthritis, and cancer.
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Genes Linked to Inflammation, Stress may Help Tailor Treatments for Depression
Measuring inflammation and stress-response levels in the blood could potentially help towards developing personalized treatments for depression, reveals a new study.
Measuring inflammation and stress-response levels in the blood could potentially help towards developing personalized treatments for depression, reveals a new study.
Source-Medindia
