PMSBuddy.com, a site created as an online reminder service, has seen one hundred thousand men sign up for its service.
The site, which educates men on knowing when their partner is likely to be suffering pre-menstrual syndrome (PMS), is the brainchild of a 28-year-old man who has gone through most of the different phases with his partners.
The reminders include pithy messages of encouragement such as "She's on yellow - tread carefully, fella" - as well as tips for how men can mitigate the damage.
It tells men never to ask if a woman has PMS, and if all else fails to buy flowers, deemed to be "kryptonite to PMS."
CEO and founder Jordan Eisenberg developed PMSbuddy.com after friends talked about the world-class diplomacy men needed to bring up the topic of PMS with their partners.
"It's hard for guys to know if they did something to piss of their lady and hard to remember when PMS is, and always awkward to confront and ask the question without coming off like a jerk," News.com.au quoted him as saying.
"One of the guys actually kept track in his daily planner, and from there we decided to automate this process and offer it to the masses," he said.
He also admitted that while functionality is first and foremost, some women may find the idea of their cycles being 'tracked' a little offensive.
"Certainly some do, but the majority do feel it is helpful, and the remainder at least get a kick and a laugh out of it," Eisenberg said.
"Those in relationships have been overwhelmingly supportive and many have actually signed themselves up to warn their boyfriends (or) husbands. If anything, we feel we can minimise unnecessary fights by allowing men to offer some slack," he added.
PMSBuddy started nine months ago and is now tracking the menstrual cycles of more than 100,000 women worldwide, including 4000 in Australia and 1000 in New Zealand via the site and a Facebook application.
Eisenberg says the site's fan base is growing rapidly and has plans to launch an iPhone application in the immediate future.