login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
Study Identifies Gene Behind Pregnancy Loss and Disorders
The condition, called aneuploidy, is an abnormal number of chromosomes.
The researchers found that if a mother's egg cell has a mutation in just one copy of Bub1 gene, then she is less likely to have offspring that survive to birth.
Dr. Sundar Venkatachalam was originally studying the gene for a possible connection to colon cancer, when he found his lab mice showed strange fertility characteristics.
"Where you would normally expect a female to have eight to 10 pups, there were only one or two pups that survived to term in the litters of females that had one copy of Bub1. So this was unusual when we were looking for cancer effects, especially in this group of females," said Venkatachalam.
Ordinarily, both copies of a gene in a chromosome must carry the same mutation in order for an organism to be adversely effected, but the drastic effects of a single mutation were unexpected.
The researchers also found that the harmful effects of this mutation increased with a mother's age.
As the female mice got older, there was eventually a complete loss of their ability to support a full-term pregnancy that lined up with an increase in aneuploidy.
|
|
|
More News on: Pregnancy and Diet , DNA Finger Printing, Trimester of pregnancy, Pregnancy and Exercise, Home Pregnancy Test, Pregnancy, Psychological Changes In Pregnancy, Ovulation Calculator, Pregnancy Due Date Calculator, Pregnancy Confirmation Calculator
 Comment & Contribute
|
Medwonders Health Network
- Health News Index
 | Quiz on Pregnancy Does morning sickness tire you? Learn useful tips from the pregnancy quiz. 
|
- News Quick Links
 |
Pregnancy
Complete Medindia Resources
|
| News Categories: |
| » | Schizophrenia Drug Differentiates Cancer Stem Cells into Less Threatening Cells |
| » | Docs Who Seldom Meet Drug Reps Continue to Prescribe Drugs With FDA “Black Box” Warnings |
| » | Revision in Quality Standards for Heparin |
| » | Acne Drug Users At High Risk of Developing Eye Infections |
| » | Patients Who Take Antidepressants When in ICU More Likely to Die |
| More Drug News | |
|
