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Quit Smoking? Impact Lingers!
In a separate smoking-related study also released today, "Smoking Cessation and the Risk for Advanced Neoplasia: Risk for Women Persists Longer than for Men," researchers from the University of Connecticut found that the risk of advanced pre-cancerous tissue changes (neoplasia) was significantly elevated for women —even if they stopped smoking—but not for men--suggesting that the impact of smoking in women has a longer effect than in men.
In the study, "Cigarette Smoking Impairs Pancreatic Duct Cell Function," researchers from Center for Pancreatic Disease at Brigham and Women's Hospital in Boston assessed pancreatic duct cell function in smokers and non-smokers (current and past). A total of 131 subjects (74 smoked and 57 never smoked) underwent secretin-stimulated endoscopic pancreatic function testing (ePFT), for pancreatic fluid bicarbonate analysis. Cigarette smoking exposure was found to be associated with an abnormal ePFT result, and there was no statistical difference in peak bicarbonate concentration between current and former smokers, according to the results.
The risk of pancreatic duct cell dysfunction was 56.78 percent in former or current smokers and 26.32 percent in nonsmokers, according to Vivek Kadiyala, MD, who presented the findings. "Our data suggests the risk of duct cell dysfunction was doubled in patients who smoked compared to nonsmokers," said Dr. Kadiyala.
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