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Physical Activity Keeps You Free from Gallstones
February 14, 2008 at 7:39 PM
General Health News
The finding is based on a study by researchers at University of Illinois who showed that exercise-trained mice are less susceptible to gallstones than inactive mice.
The study led by Kenneth Wilund, a faculty member in the U of I Division of Nutritional Sciences and an Assistant Professor in Kinesiology and Community Health has identified potential mechanisms to explain the reason behind this phenomenon.
For the first time, we have direct evidence that physical activity reduces gallstone formation, adding to the ever-increasing number of reasons that people should get more exercise, said Wilund
He also said that gallstones are formed when bile cholesterol levels become high enough to precipitate, fall out of solution, and solidify.
For the study, the researchers fed 50 mice from a gallstone-susceptible strain with a high-fat diet containing cholic acid, helping to increase cholesterol absorption. Later, they were divided into two groups: One group of mice ran on treadmills 45 minutes per day five days a week; the other group did not exercise.
12 weeks later, the researchers took out the animals gallbladders, pooling the stones from each group and weighing them. It was found that the gallstones in the sedentary group weighed two and a half times more than the stones in the exercised group.
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