login
Become a member
Quick Registration
Full Registration Benefits -
Free Homepages for Doctors
Free Homepages for Hospitals
Free Homepages for Medical Conference
Free Homepages for NGO's
Personal Health Record Creation
Access to all Medical Slides
Access to all Jobs & Products Sale
HLHS Influenced by Genetic Factors Say Researchers
October 11, 2007 at 4:55 PM
Genetics & Stem Cells News
The researchers found that the malformation has high heritability, suggesting that families with a child with HLHS carry a significant recurrence risk.
“Our study demonstrates that HLHS has high heritability, suggesting it is caused almost entirely by genetic effects instead of environmental factors, and that families with a child with HLHS carry a significant recurrence risk of HLHS or related heart defects. This should be considered by physicians when counselling parents to ensure they are aware of potential risks,” said the lead author of the study, Robert B. Hinton, Jr., M.D., a physician.
The study conducted at Cincinnati Children’s Hospital Medical Center included 38 family-based test groups with a history of HLHS.
The authors of the study found that 55 percent of those families had one or more blood relative with HLHS or an associated heart defect. Of 193 blood relatives evaluated between the ages of 3 days and 74 years, 21.4 percent had HLHS or associated heart defects.
In families where one child already had HLHS, the risk of HLHS recurring in a sibling was 8 percent while the risk of a sibling having an HLHS-associated cardiovascular defect was 22 percent. In families where a child and one parent had HLHS, the recurrence risk increased dramatically to 21 percent for recurring HLHS and 25 percent for an associated defect. All participants were evaluated using echocardiography to determine specific phenotype, or the visible heart characteristics and defects found among the different family test groups. During those examinations researchers diagnosed 12 new cases of associated defects among relatives of HLHS patients.
|
|
|
More News on: Genetics and Stem Cells
 Comment & Contribute
|
Medwonders Health Network
- Health News Index
- News Quick Links
| News Categories: |
| » | Research: Bright Colored Chips can Cut Consumption by Half |
| » | Olympic Athlete's Body Via the 80-10-10 Raw Vegan Diet |
| » | Importance of Canned Foods To Help Tackle IOM Weight Of The Nation Recommendations, Highlights Study |
| » | US Rules Pomegranate Juice Claims Deceptive |
| » | Reducing Entrée Size Could Increase Fruit and Vegetable Intake in Children |
| More Diet News | |
|
