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Side effect(s) of Acetaminophen and Oxycodone


Review the side-effects of Acetaminophen and Oxycodone as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

   Serious
- Respiratory depression, difficulty in breathing, respiratory arrest, circulatory depression, low blood pressure and shock.

   Body as a Whole
- Severe allergic reactions, uneasiness, weakness, fatigue, chest pain, fever, chills, thirst, headache and increased sweating.

  Heart
- High blood pressure, fast/slow heart rate and palpitations.

   Central Nervous System
- Lack of consciousness, tremor, tingling, drowsiness, seizures, epilepsy, anxiety, mental impairment, agitation, swelling of the brain, confusion, dizziness, sleeplessness, nervousness, hallucinations, depression, suicidal thoughts and drug abuse.

   Gastrointestinal
- Indigestion, taste disturbances, abdominal pain, enlarged abdomen, increased sweating, diarrhea, dry mouth, flatulence, gastrointestinal disorders, nausea, vomiting, inflammation of pancreas, intestinal obstruction and constipation.

   Liver
- Liver failure and jaundice.

   Eye and ENT
- Hearing loss, ringing in the ear, visual disturbances and redness of eye.

   Blood
- Decreased platelet count.

   Metabolic
- Decreased/increased sugar level in blood, acidity, alkalosis and dehydration.

   Musculoskeletal
- Muscle pain and weakness.

   Respiratory
- Asthma, lung swelling, bronchospasm, respiratory arrest, respiratory depression, pulmonary edema, laryngeal edema and shallow/fast breathing.

   Skin and Appendages
- Redness, rash, flushing and hives.

   Genitourinary
- Liver inflammation, papillary necrosis, protein in urine, kidney insufficiency, kidney failure and urinary retention.

Other Precautions :

If condition worsens consult with your doctor.
Avoid excess dosage.

Drug Name : Acetaminophen and Oxycodone

Acetaminophen and oxycodone is a combination of pain-relieving medications including non-opioid and narcotic or sleep-inducing drugs help to relieve moderate to severe pain. Acetaminophen or paracetamol increase the pain-relieving effects of oxycodone.


Trade Names for Acetaminophen and Oxycodone

International :


Percocet, Roxicet, Tylox, Oxycet, Roxilox
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