Medindia » Medication Manual » Teriflunomide

Teriflunomide

Latest prescription information about Teriflunomide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Teriflunomide
Trade Name(s): 
International- Aubagio.
Why it is prescribed (Indications) : This medication is a pyrimidine synthesis inhibitor prescribed for multiple sclerosis. 
When it is not to be taken (Contraindications): Contraindicated in patients with severe liver impairment, who are taking leflunomide and during pregnancy.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : Adult- PO- The recommended dose is 7mg or 14mg once daily.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver or kidney disease, fever, infection, diabetes, breathing problems, high blood pressure, elderly and breastfeeding women.
* Monitor kidney function and potassium level regularly while taking this medication.
* It may increase WBC counts; monitor complete blood counts regularly while taking this medication.
* Patient may develop with peripheral neuropathy; if it is so consult with your healthcare provider.
Side Effects : 
Most Common- Hair loss, increased level of liver enzymes, diarrhea, influenza, nausea, and tingling.
Infections and Infestations - Influenza, upper respiratory tract infection, bronchitis, sinusitis, cystitis, gastroenteritis viral, oral herpes.
Blood - Decrease in white blood cells.
Central Nervous System - Headache, anxiety, tingling, sciatica, burning sensation, carpal tunnel syndrome.
Eye - Vision blurred, eye inflammation.
Heart - Palpitations, high blood pressure.
Gastrointestinal - Abdominal pain upper, toothache, abdominal distension.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature between (20°C to 25°C).

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z