Generic Name : Teriflunomide
International- Aubagio. Why it is prescribed (Indications) : This medication is a pyrimidine synthesis inhibitor prescribed for multiple sclerosis. When it is not to be taken (Contraindications): Contraindicated in patients with severe liver impairment, who are taking leflunomide and during pregnancy.
Dosage & When it is to be taken : Adult- PO- The recommended dose is 7mg or 14mg once daily. How it should be taken : It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of liver or kidney disease, fever, infection, diabetes, breathing problems, high blood pressure, elderly and breastfeeding women.
* Monitor kidney function and potassium level regularly while taking this medication.
* It may increase WBC counts; monitor complete blood counts regularly while taking this medication.
* Patient may develop with peripheral neuropathy; if it is so consult with your healthcare provider. Side Effects :
Most Common- Hair loss, increased level of liver enzymes, diarrhea, influenza, nausea, and tingling.
Infections and Infestations - Influenza, upper respiratory tract infection, bronchitis, sinusitis, cystitis, gastroenteritis viral, oral herpes.
Blood - Decrease in white blood cells.
Central Nervous System - Headache, anxiety, tingling, sciatica, burning sensation, carpal tunnel syndrome.
Eye - Vision blurred, eye inflammation.
Heart - Palpitations, high blood pressure.
Gastrointestinal - Abdominal pain upper, toothache, abdominal distension.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature between (20°C to 25°C).
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