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Sunitinib
Latest prescription information about Sunitinib. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Sunitinib
Pronunciation : SOO-NI-ti-nib
Trade Name(s):
International- Sutent. This medication is a multikinase inhibitor, prescribed for gastrointestinal stromal tumor, renal cell carcinoma (RCC), and pancreatic neuroendocrine tumors (pNET). When it is not to be taken (Contraindications):
When it is to be taken : For gastrointestinal stromal tumor renal cell carcinoma- Adult- PO- The recommended dose is one 50 mg once daily, on a schedule of 4 weeks on treatment followed by 2 weeks off. For pancreatic neuroendocrine tumors -The recommended dose is 37.5 mg taken orally once daily continuously without a scheduled off-treatment period. How it should be taken : It comes as a capsule to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of bleeding problem, chest pain, slow, fast, or irregular heartbeat, heart attack, heart failure, high blood pressure, pulmonary embolism (PE; blood clot in the lungs), transient ischemic attack (TIA) (mini-stroke), seizures, stroke, kidney, liver, or thyroid disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * It may reduce platelet counts; avoid bruising or injury. * Avoid contact with people who have infections in order to prevent the spread of infection. * Monitor complete blood cell counts, blood electrolytes, blood pressure checks, thyroid function, liver function, and electrocardiograms (ECG) and other heart function regularly while taking this medication. Side Effects : Most Common - Fatigue, weakness, fever, diarrhea, nausea, mouth ulcer, vomiting, indigestion, abdominal pain, constipation, high blood pressure, swelling in the extremities, rash, hand-foot syndrome, skin discoloration, dry skin, hair color changes, altered taste, headache, back pain, joint pain, cough, difficulty in breathing, loss of appetite, and bleeding. Gastrointestinal - Dry mouth, reflux, flatulence, mouth pain, burning tongue, and piles. Heart - High blood pressure, fluid retention, and chest pain. Skin - Hair loss, redness, and itching. Central Nervous System - Dizziness, depression, and sleeplessness. Musculoskeletal - Limb discomfort. Endocrine - Thyroid deficiency. Respiratory - Throat pain and upper respiratory tract infection. * Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (25°C). |
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