Information about Sargramostim

Generic Name : Sargramostim
Up-to-date prescription details regarding Sargramostim are provided here.

Pronunciation : sar-GRA-moe-stim

Learn the correct pronunciation of the Sargramostim, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Sargramostim

EMGRAST-M vial

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International :

Leukine

Why is Sargramostim Prescribed? (Indications)

This medication is a hematopoietic agent, prescribed for severe, life-threatening infections after chemotherapy for acute myelogenous leukemia (AML). It is also used for bone marrow transplantation. It stimulates the production of white blood cells in bone marrow.

When should Sargramostim not be taken? (Contraindications)

Contraindicated in patients with certain bone marrow disorders, concomitant use with chemotherapy and radiotherapy, and hypersensitivity.

What is the dosage of Sargramostim?

IV/SC- The recommended dose is 250mcg/m²/day, over a 4-hour infusion. Start approximately on day 11 or four days following the completion of induction chemotherapy.

How should Sargramostim be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein or under the skin.

What are the warnings and precautions for Sargramostim?

• Caution should be exercised in patients with history of fluid retention, irregular heartbeat, lung disorder or breathing problems, heart, liver or kidney disease, cancer, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may affect blood sugar level; monitor sugar level regularly while taking this medication.

• Monitor liver function, kidney function, blood counts, body weight, fluid and electrolyte level regularly while taking this medication.

What are the side effects of Sargramostim?

General - Fever, headache, swelling in the extremities, chills, weakness, chest pain, fluid retention, abdominal pain, and back pain.
Metabolic - Increase or decrease in liver enzymes and increased sugar.
Gastrointestinal - Diarrhea, nausea, vomiting, mouth ulcer, indigestion, gastrointestinal bleeding, constipation, difficulty in swallowing and loss of appetite.
Respiratory - Inflammation of pharynx, nosebleed, difficulty in breathing and nose inflammation.
Blood - Blood vomiting, decrease in white blood cells, platelets.
Genitourinary - Blood in urine.
Skin - Rash, hair loss and itching.
Central Nervous System - Tingling, anxiety and sleeplessness.
Musculoskeletal - Bone pain and joint pain.
Eye - Eye bleeding.
Heart - High blood pressure, high cholesterol and fast heart rate.