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Sargramostim

Latest prescription information about Sargramostim. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Sargramostim
Pronunciation : sar-GRA-moe-stim
Therapeutic Classification : psychotherapeutics
Trade Name(s): 
International- Leukine.
Why it is prescribed (Indications) : 
This medication is a hematopoietic agent, prescribed for severe, life-threatening infections after chemotherapy for acute myelogenous leukemia (AML).It is also used for bone marrow transplantation.

When it is not to be taken (Contraindications): 


Contraindicated in patients with certain bone marrow disorders, concomitant use with chemotherapy and radiotherapy, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
IV/SC- The recommended dose is 250mcg/m²/day, over a 4-hour infusion. Start approximately on day 11 or four days following the completion of induction chemotherapy.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein or under the skin.
Special Instruction : 
* Caution should be exercised in patients with history of fluid retention, irregular heartbeat, lung disorder or breathing problems, heart, liver or kidney disease, cancer, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It may affect blood sugar level; monitor sugar level regularly while taking this medication.
* Monitor liver function, kidney function, blood counts, body weight, fluid and electrolyte level regularly while taking this medication.
Side Effects : 
General - Fever, headache, swelling in the extremities, chills, weakness, chest pain, fluid retention, abdominal pain, and back pain.
Metabolic - Increase or decrease in liver enzymes and increased sugar.
Gastrointestinal - Diarrhea, nausea, vomiting, mouth ulcer, indigestion, gastrointestinal bleeding, constipation, difficulty in swallowing and loss of appetite.
Respiratory - Inflammation of pharynx, nosebleed, difficulty in breathing and nose inflammation.
Blood - Blood vomiting, decrease in white blood cells, platelets.
Genitourinary - Blood in urine.
Skin - Rash, hair loss and itching.
Central Nervous System - Tingling, anxiety and sleeplessness.
Musculoskeletal - Bone pain and joint pain.
Eye - Eye bleeding.
Heart - High blood pressure, high cholesterol and fast heart rate.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2-8°C). Do not freeze it.

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