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Drug information on EMGRAST-M vial (Sargramostim) from Emcure Pharmaceuticals Ltd. (Gennova)


Emcure Pharmaceuticals Ltd. (Gennova)
Generic : Sargramostim

Drug Name : Sargramostim

Sargramostim(Leukine) generic EMGRAST-M vial is a hematopoietic agent, prescribed for severe, life-threatening infections after chemotherapy for acute myelogenous leukemia (AML). It is also used for bone marrow transplantation. It stimulates the production of white blood cells in bone marrow.
More Info about Sargramostim

Dhanalakshmi Chinnuswamy
Further Checked by The Medindia Medical Review Team on February, 2, 2017
Medindia currently has information on 3080 generic drugs and 110,061 brands that have their prices listed. New drugs with their prices are listed as and when they get approved by the drug controller. Please do write to us ( if a drug is missing from our comprehensive drug price list.

Medical Condition(s) for which EMGRAST-M vial may be prescribed

Side effects of EMGRAST-M vial

   General : Fever, headache, swelling in the extremities, chills, weakness, chest pain, fluid retention, abdominal pain, and back pain.

   Metabolic : Increase or decrease in liver enzymes and increased sugar.

   Gastrointestinal : Diarrhea, nausea, vomiting, mouth ulcer, indigestion, gastrointestinal bleeding, constipation, difficulty in swallowing and loss of appetite.

   Respiratory : Inflammation of pharynx, nosebleed, difficulty in breathing and nose inflammation.

   Blood : Blood vomiting, decrease in white blood cells, platelets.

   Genitourinary : Blood in urine.

   Skin : Rash, hair loss and itching.

   Central Nervous System : Tingling, anxiety and sleeplessness.

   Musculoskeletal : Bone pain and joint pain.

   Eye : Eye bleeding.

   Heart : High blood pressure, high cholesterol and fast heart rate.

Dosage & When it is to be taken (Indications)

IV/SC- The recommended dose is 250mcg/m²/day, over a 4-hour infusion. Start approximately on day 11 or four days following the completion of induction chemotherapy.

How to use EMGRAST-M vial?

It comes as a solution for injection to be administered by a healthcare provider into the vein or under the skin.

When is EMGRAST-M vial not to be taken? (Contraindications)

Contraindicated in patients with certain bone marrow disorders, concomitant use with chemotherapy and radiotherapy, and hypersensitivity.

Warnings and Precautions for EMGRAST-M vial

Caution should be exercised in patients with history of fluid retention, irregular heartbeat, lung disorder or breathing problems, heart, liver or kidney disease, cancer, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may affect blood sugar level; monitor sugar level regularly while taking this medication.

• Monitor liver function, kidney function, blood counts, body weight, fluid and electrolyte level regularly while taking this medication.

Other Precautions for EMGRAST-M vial

Avoid excess dosage.

Storage Conditions for EMGRAST-M vial

Store it in refrigerator (2-8°C). Do not freeze it.

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For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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