Trade Names/Brand Names :
Esoterica and Melquin
Why it is prescribed :
Hydroquinone is a local cream prescribed for dark or hyper-pigmented skin marks such as freckles (small flat brown marks on the face and sun exposed areas), melasma (brown patches on skin), age spots, and dark spots due to acne, pregnancy-related scars, skin trauma or use of birth control pills. It works by inhibiting tyrosinase, enzyme which is required to make melanin in skin cells. Melanin give the skin the dark color.
When it is not to be taken (Contraindications):
Hydroquinone cream should not be used during pregnancy or in patients allergic to the drug. It is not recommended for children 12 years or below.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Adult:Local application as 2-4% cream. Apply twice daily on the affected site.
How it should be taken :
Gently rub the cream topically on the skin until it is evenly distributed. It comes as a cream to apply topically.
Warnings and Precautions :
•Caution should be exercised in patients with history of asthma, any allergy, elderly, children, during pregnancy and breastfeeding.
Avoid contact with eyes , mouth and other mucous membranes.
Avoid using this cream on open wounds or other skin conditions like eczema and psoriasis.
Avoid exposure of the affected skin to direct sunlight.
Side Effects :
Mild burning, stinging,tingling, redness, dryness, itching, pimples, rash. Some of the serious effects include blistering, cracking of the skin and ochronosis (bluish black pigmentation on the skin).
Other Precautions :
Stop the medication if there is no improvement after 3 months of treatment.
Drug Interactions :
Hydroquinone should be avoided with:
• Hydrogen peroxide ,benzoyl peroxide or other peroxide containing products,since it can cause skin darkening.
Storage Conditions :
Store it at room temperature (20°-25°C), keep away from light and moisture.