Cytarabine - Drug Information

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General Information on Cytarabine

Generic Name : Cytarabine

Pronunciation : sye tare' a been

Latest prescription information about Cytarabine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Why is Cytarabine Prescribed? (Indications)

This medication is a chemotherapy agent, prescribed for acute myeloid leukemia (AML) and non-Hodgkin lymphoma. This medication slows the growth and spread of cancer cells in the body.  

When should Cytarabine not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category D :

There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.

What is the dosage of Cytarabine?

IV/SC- The recommended dose is 100 mg/m2/day (days 1 to 7) or 100 mg/m2 IV every 12 hours (days 1 to 7).

How should Cytarabine be taken?

It comes as a solution for injection to be administered by a healthcare into the vein.

What are the warnings and precautions for Cytarabine?

Caution should be exercised in patients with history of liver and kidney dysfunction, severe infections, preexisting drug-induced bone marrow suppression, any allergy, who are taking other medications, children, during pregnancy and breast-feeding.
It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
It may decrease platelet counts, which leads to severe bleeding; avoid injury or bruising.
Monitor complete blood cell counts, liver and kidney functions regularly while taking this medication.
Avoid drinking alcoholic beverages and citrus fruit juices.

What are the side effects of Cytarabine?

   Most Common : Bone marrow suppression, loss of appetite, nausea, vomiting, diarrhea, mouth ulcer, fever and rash.
   Central Nervous System : Headache, dizziness, seizures, drowsiness, depression, anxiety, coma, incoordination, speech disorder and vision loss.
   Respiratory : Lung swelling and cough.
   Musculoskeletal : Muscle pain, neck pain and muscle stiffness.
   Genitourinary : Increased urinary retention.
   Eye : Blurred vision.
   Skin : Increased sweating.

What are the other precautions for Cytarabine?

Avoid excess dosage.

What are the storage conditions of Cytarabine?

Store it at controlled room temperature (25C).

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