Generic Name : Cytarabine Pronunciation : sye tare' a been
Therapeutic Classification : Chemotherapy Trade Name(s):
India- Arasid Vial, Biobin Inj, Cancyt Vial, Cybin-Pf Vial, Cytabin Vial, Cytalon Inj, Cytarabin Inj, Cytarabine Vial, Cytaraside Vial, Cytarine Vial, Cytrosar Vial, Oncotar Vial, Remcyta Vial, Zecyte Inj.
International- Cytosar-U, DepoCyt. Why it is prescribed (Indications) :
This medication is a chemotherapy agent, prescribed for acute myeloid leukemia (AML) and non-Hodgkin lymphoma. This medication slows the growth and spread of cancer cells in the body. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
IV/SC- The recommended dose is 100 mg/m2/day (days 1 to 7) or 100 mg/m2 IV every 12 hours (days 1 to 7). How it should be taken :
It comes as a solution for injection to be administered by a healthcare into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of liver and kidney dysfunction, severe infections, preexisting drug-induced bone marrow suppression, any allergy, who are taking other medications, children, during pregnancy and breast-feeding.
* It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
* It may decrease platelet counts, which leads to severe bleeding; avoid injury or bruising.
* Monitor complete blood cell counts, liver and kidney functions regularly while taking this medication.
* Avoid drinking alcoholic beverages and citrus fruit juices. Side Effects :
Most Common - Bone marrow suppression, loss of appetite, nausea, vomiting, diarrhea, mouth ulcer, fever and rash.
Central Nervous System - Headache, dizziness, seizures, drowsiness, depression, anxiety, coma, incoordination, speech disorder and vision loss.
Respiratory - Lung swelling and cough.
Musculoskeletal - Muscle pain, neck pain and muscle stiffness.
Genitourinary - Increased urinary retention.
Eye - Blurred vision.
Skin - Increased sweating.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (25°C).
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