Allopurinol - Drug Information

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Generic Name : Allopurinol

Pronunciation : (al oh pure'i nole)

Latest prescription information about Allopurinol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Gout Therapy

Trade Names/Brand Names : 

India : 

More...

International : 

Zyloprim

Why it is prescribed : 

This medication is a xanthine oxidase inhibitor, prescribed for gout. It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy. 

When it is not to be taken (Contraindications): 

Hypersensitivity.

Pregnancy Category :


A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

Dosage & When it is to be taken (Indications): 

Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2/day. Max: 600 mg/day.

How it should be taken : 

It comes as a tablet to take by mouth, with food.

Warnings and Precautions : 

Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
Monitor kidney and liver function regularly while taking this medication.


Side Effects : 

   Gastrointestinal : Diarrhea, nausea and increased level of liver enzymes.
   Metabolic : Acute attacks of gout.
   Skin : Rash.

Other Precautions : 

Avoid excess dosage.
Follow the diet and exercise program as directed by your physician.

Storage Conditions : 

Store it at controlled room temperature (15 to 25C) and in an airtight container.

Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.


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Prashant_P 

I have high uric acid[=7.7]. I have pain below heel in both legs. I have taken Zyloric for 2 months and uric acid is reduced from 9 to 7.7. But no improvement in heel pain. Please guide.

raju.com 

I an 70 year old. I have been taking one tablet of Zyloric for the last more than 10 years. My uric acid is up to 5. I have no other symptoms. Now for the last two months I have developed acute pain in my back radiating to calf muscles [left side]. My MRI report is normal excepting for age related changes. I am feeling better with medication. I want to reduce the intake of Zyloric now to alternate days. Should I do it.

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