Trade Names/Brand Names :
Why it is prescribed :
This medication is a xanthine oxidase inhibitor, prescribed for gout. It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy.
When it is not to be taken (Contraindications):
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2
/day. Max: 600 mg/day.
How it should be taken :
It comes as a tablet to take by mouth, with food.
Warnings and Precautions :
• Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
Monitor kidney and liver function regularly while taking this medication.
Side Effects :
Diarrhea, nausea and increased level of liver enzymes.
Acute attacks of gout.
Other Precautions :
Avoid excess dosage.
Follow the diet and exercise program as directed by your physician.
Storage Conditions :
Store it at controlled room temperature (15° to 25°C) and in an airtight container.
Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.