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Medindia » Medication Manual » Allopurinol

Allopurinol

Latest prescription information about Allopurinol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Allopurinol

Pronunciation : (al oh pure'i nole)

Therapeutic Classification : Gout Therapy

Trade Name(s):
India- Aligout Tab, Allgoric Tab, Aloric Tab, Aloriv Tab, Aluno-A Tab, Alur Tab, Alurid Tab, Biorinol Tab, Burin Tab, Ciploric Tab, Edorin Tab, Gurik Tab, Lodiric Suscap, Lodiric Tab, Logout-Sr Suscap, Orlu Tab, Piloric Tab, Purinol Tab, Satric Tab, Swiloric Tab, Urlo Tab, Z-Nol Tab, Zyloric Tab, Zyprinol Sr-Cap, Zyprinol Tab, Zytol Dispertab .
International- Zyloprim.

Why it is prescribed (Indications) :
This medication is a xanthine oxidase inhibitor, prescribed for gout. It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy.

When it is not to be taken (Contraindications):
Hypersensitivity.

Pregnancy Category :

A B C D X

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken :
Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m²/day. Max: 600 mg/day.

How it should be taken :
It comes as a tablet to take by mouth, with food.

Warnings and Precautions :
* Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
* It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
* Monitor kidney and liver function regularly while taking this medication.

Side Effects :
Gastrointestinal - Diarrhea, nausea and increased level of liver enzymes.
Metabolic - Acute attacks of gout.
Skin - Rash.

Other Precautions :
* Avoid excess dosage.
* Follow the diet and exercise program as directed by your physician.

Storage Conditions :
Store it at controlled room temperature (15° to 25°C) and in an airtight container.

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Posted by: Ashish1274, India Posted on: 11/26/2012 I have problem of high uric acid since last three years with pain on right foot toe. the pain is unbearable. it subsides when i take zyloric 100.but after 3 month or so the uric acid level increases again with pain. Kindly help me to get over the problem comletely. My Blood sugar level keeps little high,and i have modified my diet to exclude red meat,sea food,Alcohol in very limited quantity, palak, tomato, pulses etc
Posted by: nary123, India Posted on: 10/26/2012 Sir, I have problem of high uric acid since last three years with pain on right foot toe. the pain is unbearable. it subsides when i take zyloric 100.but after six month or so the uric acid level increses again with pain. Kindly help me to getover the problem comletely.my Blood sugar level is normal,and i have modified my diet to exclude red meat,sea food,Alcohol in very limited quantity, palak, tomato, pulses etc.
Posted by: sahmad2003, Pakistan Posted on: 8/31/2012 It is very effective for kidney stone as well as crystall.but i have problem after taking the tab.zyloric 100mg gaining weigh persistently from last one year or so.its side also to hold the water inside the body?????????? Dr Syed Pakistan
Posted by: PKKARAN, India Posted on: 2/27/2012 This site is very very beneficial to the patient,Students,Doctors to gather adequate knowledge. Thanks a lot, Yours P.K.Karan
Posted by: raman, India Posted on: 9/14/2008 It is very effective for kidney stone. It is my experience 7 m.m renal calculi was diluted and passed through the urine with the effect of the allopurinol (allgoric)...
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