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 Medindia » Consumer Health » Medication Manual » Allopurinol

Allopurinol

Latest prescription information about Allopurinol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Allopurinol
Pronunciation : (al oh pure'i nole)
Trade Name(s): 
India- Aligout Tab, Allgoric Tab, Aloric Tab, Aloriv Tab, Aluno-A Tab, Alur Tab, Alurid Tab, Biorinol Tab, Burin Tab, Ciploric Tab, Edorin Tab, Gurik Tab, Lodiric Suscap, Lodiric Tab, Logout-Sr Suscap, Orlu Tab, Piloric Tab, Purinol Tab, Satric Tab, Swiloric Tab, Urlo Tab, Z-Nol Tab, Zyloric Tab, Zyprinol Sr-Cap, Zyprinol Tab, Zytol Dispertab .
International- Zyloprim.
Why it is prescribed (Indications) : 
This medication is a xanthine oxidase inhibitor, prescribed for gout. It is used to treat high uric acid levels in the blood or urine caused by certain types of cancer chemotherapy.

When it is not to be taken (Contraindications): 


Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: PO- Gout and Hyperuricaemia- Initial: 100 mg/day, may adjust dose according to response. Max: 800 mg/day.
Prevention of hyperuricaemia associated with chemotherapy treatment or enzyme disorders- 600-800 mg/day, starting 2-3 days before cancer treatment.
IV- Gout and Hyperuricaemia: As Na: 200-400 mg/m2/day. Max: 600 mg/day.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Special Instruction : 
* Caution should be exercised in patients with history of kidney or liver diseases, heart problems, bone marrow problems, high blood pressure, diabetes, who are taking other medication, any allergy, children, during pregnancy and breastfeeding.
* It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
* Monitor kidney and liver function regularly while taking this medication.
Side Effects : 
Gastrointestinal - Diarrhea, nausea and increased level of liver enzymes.
Metabolic - Acute attacks of gout.
Skin - Rash.
Other Precautions : 
* Avoid excess dosage.
* Follow the diet and exercise program as directed by your physician.
Storage Conditions : 
Store it at controlled room temperature (15° to 25°C) and in an airtight container.

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Member Comments ( 3 )
It is very effective for kidney stone. It is my experience 7 m.m renal calculi was diluted and passed through the urine with the effect of the allopurinol (allgoric)...
(Posted by raman, India Date : 9/14/2008 )
I live in Hanoi, Vietnam. I want to buy some bottle of Allopurinal.So, I want to know whether I can buy this medicine in Vietnam or not? I look forward to your soon reply. Thank you very much! Bui Thi Huyen
(Posted by Bui Thi Huyen, Viet Nam Date : 7/16/2008 )
Sir, I have problem of high uric acid (7.9) with pain on right foot toe. This was an unbearable pain when started. A week back I had this problem second time within 2 years. I am using ciploric 300 now after lunch & 3 lts of water intake daily from last 10 days back now. Kindly guide me more to prevent further attacks.Blood sugar level is slightly more than normal (fasting & PP). I use 300 mls milk, two spoons sugar, a little Dal, alcohol rarely, some chicken fortnightly,4 chapatis, lunch & dinner with vegetables / Rice No noticeable side affects
(Posted by Umesh Kumar Khindri, India Date : 3/26/2008 )

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