A biological ability to compensate for the body's reduced response to insulin may explain why women typically develop heart disease 10 years later than men.
This is according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).
Insulin is a hormone that takes glucose from the bloodstream and carries it into cells, where it is used for energy. When the body doesn't use insulin properly, a condition known as insulin resistance, it raises the risk a person will develop diabetes and cardiovascular disease.
The cross-sectional study examined insulin resistance and cardiovascular disease risk in 468 women and 354 men. Among participants ages 50 or younger, women had lower blood pressure and fasting blood sugar levels than their male counterparts. In addition, women had lower levels of triglycerides, fats in the blood that can increase the risk of heart disease and stroke.
"The findings suggest young women are uniquely equipped to offset the negative effects of insulin resistance," Kim said. "Although there is no difference in the level of insulin resistance between genders, young women are still able to avoid the worst complications from insulin resistance."
Kim theorizes this may be a natural form of protection for women in their reproductive years, but additional research needs to be done in this area.