Their anti-ageing cream worked famously, consumers emptied supermarket shelves in no time.
Now the UK based Boots has launched its Protect & Perfect Body Serum, designed for use on a much wider area.
The product is the work of scientist Steve Barton, Boots's skincare scientific adviser. He said the product had been well-received in consumer trials.
It also contains some of the same peptides and other ingredients that made its facial product a success.
Unlike the facial serum, which is intended for use under a moisturiser, the body serum is intended to be used alone.
Advertising for the product claims that: "Day by day, it refines texture, evens out skin tone, gives a firmer appearance and restores luminosity, so that after four weeks, skin looks noticeably firmer and more radiant."
However, the most important question for customers will be whether the new product - priced at £25 for 200ml - actually helps turn back time
Barton, who has a degree in biology and a masters on host nutrition and parasite development, says that for best results customers should still apply sunscreen and choose cleansing products suited to their skin type.
Boots are expecting the newest product to emulate the success of the face cream.
Since March 4.15million bottles have been sold - the equivalent to one every four seconds. Boots says it has sold the equivalent of 62 years worth of stock in six months. Such was the demand that in early June, etched glass bottles were replaced with plastic tubes.
Obviously Boots are hoping for an encore.
However, it has not yet received the benefit of the same independent testing on its scientific benefits.
Experts believe the serum will have the best results on more exposed parts such as the neck and décolletage, as well as arms and legs.