Weight changes are associated with reduced bone strength, revealed researchers from Hebrew SeniorLife's Institute for Aging Research, Boston University, Beth Israel Deaconess Medical Center, and University of Calgary. The results were published in the Journal of Bone and Mineral Research.
Douglas P. Kiel, MD, MPH, principal investigator for the study said, "The study is significant because it used data on weight changes over 40 years in participants in the Framingham Study. We showed that men and women with both shorter term weight loss over 4-6 years and longer term weight loss over 40 years had more micro-architectural deterioration of their bones than persons who did not lose weight."
The magnitude of changes to the skeleton were clinically significant and translated into an almost three-fold increase in the risk of fracture for those who lost 5% or more weight over 40 years.