The status of type 2 diabetes and its impact on the body can be measured with the presence of biological identification in the blood - HbA1c levels in the blood portray the exact status of the disease; high levels of HbA1c denotes the condition taking a turn for the worse, notwithstanding the medication for blood glucose management.
This point became evident after an exhaustive study spanning seven years that tracked 1200 patients suffering type-2 diabetes. The finding revealed that HbA1c levels had slumped from 7.6 to 6.3 percent during the first year; subsequently during the rest of the six years, the levels of HbA1c shot up from 6.3 to 7.0 percent. Additionally the patients needed insulin therapy after 2.5 years from onset of diabetes. It was also observed that after 7 years nearly 47% of the study subjects required insulin therapy. Delving into the non-genetic causes of such a phenomenon, researchers found that early onset diabetes or the age of a patient during diagnosis of the disease has a bearing on the fluctuation in HbA1 c levels over a period of time. It became clear that patients who contracted diabetes before 50 years of age experienced a sharp increase in HbA1c levels .
than the patients who were older than 50 during diagnosis. The increase in HbA1c in the blood for patients diagnosed with diabetes before 50 years of age was associated with a weakened potential of the pancreas cells to manage the production of insulin. Whether genetics can offer valuable insight in understanding this link, is an area that needs further investigation.