About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Weird Protein Puzzles Researchers

by Savitha C Muppala on September 9, 2006 at 2:53 PM
Font : A-A+

Weird Protein Puzzles Researchers

The surface of leukemia cells are thought to be inhabited by a rather peculiar protein, sobriquet as the "Frankenstein protein", which has peptides attached together in a pattern which is exactly the opposite of the code present in the DNA template. This revelation is far removed from the theory prescribed in the molecular biology textbooks.

This discovery has meant a shift in the original thinking that relied on the information that the structure of a protein is fixed by the DNA template, but now researchers feel that a bit of rearrangement does happen after the protein has been created.

Advertisement

Researchers say that the peptide sequence differs in comparison with the template sequence of DNA, in charge of encoding them. This knowledge will assist in the birth of peptide vaccines, to protect against cancer and contagious diseases. Researchers discovered that after a protein is assembled, the proteasome, which is part of the cells, is capable of changing the order of a few of the peptides.

The immune system essentially defends the body from invading cells, as soon as it senses the alien peptides on the surface of the cells. Similarly, the peptides present on the surface of a developing cancer alert the immune system, which permits the production of antigens from one single protein. Indeed, this discovery holds promise for the development of peptide vaccines.

Source: Medindia
SAV
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
H1N1 Influenza Prevention in Children: What Parents Need to Know
Dietary Factors Responsible for Dihydrotestosterone (DHT) Production and Hair Loss
Test Your Knowledge About Chromosomes?
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diet and Nutrition Tips for Athletes 

Most Popular on Medindia

How to Reduce School Bag Weight - Simple Tips A-Z Drug Brands in India Blood Pressure Calculator Accident and Trauma Care Loram (2 mg) (Lorazepam) Pregnancy Confirmation Calculator Iron Intake Calculator Post-Nasal Drip Sanatogen Find a Hospital
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Weird Protein Puzzles Researchers Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests