About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Type 1 Diabetes Increases Risk of Epilepsy

by Reshma Anand on April 1, 2016 at 4:29 PM
Font : A-A+

One of the most common lifestyle disease, diabetes has been widely reported to increase risk of other diseases such as stroke, kidney failure, skin and foot problems.

A recent research published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD) revealed that type 1 diabetes can increase the risk of epilepsy.

Advertisement

Type 1 Diabetes Increases Risk of Epilepsy
Type 1 Diabetes Increases Risk of Epilepsy

Type 1 diabetes mellitus is one of the most common autoimmune disorders in children, with a 3% annual increase in the global incidence rate since the 1980s. In recent decades, the incidence of type 1 diabetes has increased in children and adolescents, particularly those aged younger than 5 years.

Patients with diabetes are at increased risk of severe health problems and mortality. Recent studies have found that type 1 diabetes could be a risk factor for the development of epilepsy in children, though the exact underlying mechanisms remain unknown.
Advertisement

In this new study, Dr I-Ching Chou, China Medical University Children's Hospital, Taichung, Taiwan, and colleagues evaluated the relationship between type 1 diabetes and epilepsy in Taiwan. Data from the Taiwan National Health Insurance Research Database were used to conduct retrospective analyses.

The study cohort contained 2,568 patients with type 1 diabetes, each of whom was frequency-matched by sex, urbanization of residence area and index year with ten control patients without type 1 diabetes. Computer modeling was used to estimate the effects of type 1 diabetes on epilepsy risk.

In patients with type 1 diabetes, the risk of developing epilepsy was significantly higher than that in patients without type 1 diabetes. After adjustment for potential confounders, the type 1 diabetes cohort was 2.84 times more likely to develop epilepsy than the control cohort.

The authors say, "This result is consistent with those of previous studies in that epilepsy or seizures are observed in many autoimmune or inflammatory disorders and are linked to the primary disease, or secondary to pro-inflammatory processes."

Immune abnormalities, brain lesions, genetic factors and metabolic abnormalities are all potential causes for the link between type 1 diabetes and epilepsy.

They say: "In particular, both hyperglycaemia and hypoglycaemia commonly occur in elderly people with diabetes., and can alter the balance between the inhibition and excitation of neuronal networks and cause focal motor seizures. In addition, we found that younger age was associated with an increased risk of developing epilepsy. Previous studies have suggested severe hypoglycaemia, young age and early onset as critical risk factors for brain abnormalities... The current results could provide evidence to facilitate the prognosis of children with type 1 diabetes."

They conclude: "Patients with type 1 diabetes are at an increased risk of developing epilepsy. Metabolic abnormalities of type 1 diabetes, such as hyperglycaemia and hypoglycaemia, may have a damaging effect on the central nervous system and be associated with significant long-term neurological consequences. The causative factors between type 1 diabetes and the increased risk of epilepsy require further investigation."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
Quiz on Low-Calorie Diet for Diabetes
World Heart Day in 2022- Use Heart for Every Heart
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Diabetic Retinopathy Epilepsy Diabetes Diabetic Diet Otitis Media Diabetes - Essentials Febrile Fits / Febrile Convulsions Diabetes - Self-Monitoring of Blood Glucose (SMBG) Insulin Delivery Devices Diabetes and Exercise 

Most Popular on Medindia

Diaphragmatic Hernia Vent Forte (Theophylline) Daily Calorie Requirements How to Reduce School Bag Weight - Simple Tips Nutam (400mg) (Piracetam) Post-Nasal Drip Hearing Loss Calculator Blood Donation - Recipients Noscaphene (Noscapine) Color Blindness Calculator
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Type 1 Diabetes Increases Risk of Epilepsy Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests