About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Tumor and Flu Virus: Two Birds With One Drug

by Tanya Thomas on March 3, 2011 at 9:20 AM
Font : A-A+

 Tumor and Flu Virus: Two Birds With One Drug

Scientists have found that a drug, called DMXAA, originally developed as anti-tumor agent, also enhances the ability of flu vaccines to ward off this deadly virus.

Their study suggests that DMXAA could assist flu vaccines by causing the body to produce its own antiviral proteins, called interferons, which interfere with the virus's ability to spread.

Advertisement

In addition, DMXAA may be a useful antiviral therapy to treat newly emerging strains of the flu for which a vaccine has not been developed.

"We are hopeful that DMXAA or similar agents can be used ultimately to blunt the impact of yearly influenza outbreaks, and perhaps, for other virus infections as well," said Stefanie Vogel at the University of Maryland, co-author of the study.
Advertisement

In the study, Vogel and colleagues infected mice with a mouse-adapted influenza strain.

When given DMXAA three hours before or after infection and then two days later, the infection was significantly less severe.

In addition, they found that DMXAA protected cells from flu strains that are resistant to Tamiflu, one of the most advanced anti-flu drugs on the market.

These discoveries suggest that DMXAA could potentially enhance the efficacy of current flu treatments and vaccines, and perhaps treat other viruses or bacteria.

To be sure that DMXAA led to increased production of interferons, the researchers also tested it in mice that lacked a gene needed to produce interferon, and found that these mice received no benefit from DMXAA.

The study was published in the March 2011 issue of the Journal of Leukocyte Biology.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
Quiz on Low-Calorie Diet for Diabetes
World Heart Day in 2022- Use Heart for Every Heart
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Signature Drug Toxicity Tumor Markers For Cancer Diagnosis and Prognosis Swine Flu 

Most Popular on Medindia

Daily Calorie Requirements A-Z Drug Brands in India Indian Medical Journals Vent Forte (Theophylline) Accident and Trauma Care Loram (2 mg) (Lorazepam) Calculate Ideal Weight for Infants Blood Donation - Recipients Drug Side Effects Calculator Iron Intake Calculator
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Tumor and Flu Virus: Two Birds With One Drug Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests