About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Trabecular Bone Score Can be A Standalone Predictor of Fracture Risk

by Bidita Debnath on April 28, 2016 at 2:18 AM
Font : A-A+

Trabecular Bone Score Can be A Standalone Predictor of Fracture Risk

Trabecular bone score (TBS) is one of the most recent and extensively studied determinants of fracture risk. TBS, which is assessed by lumbar spine dual-energy X-ray absorptiometry (DXA) imaging, provides information about the micro-architectural deterioration of bone tissue.

Previous studies have shown that TBS predicts fracture in postmenopausal women and older men. TBS is currently used in conjunction with BMD values to enhance the predictive ability of the widely used Fracture Risk Assessment tool (FRAX), a calculator used to assess an individual's 10-year risk of major osteoporotic fracture.

Advertisement


In the largest such study to date, a team of international researchers have now validated the predictive ability of TBS using individual-level data of 17,809 men and women from 14 studies worldwide. They aimed to validate the contribution of TBS to fracture risk prediction, independent of FRAX, and to examine the impact of applying TBS adjustment to FRAX probabilities.

The study authors found that TBS was consistently an independent contributor to the assessment of fracture risk and that the relationship with other risk factors was robust across sex, diverse races, fracture incidences, and geographical regions.
Advertisement

The combination of TBS with the clinical risk factors (including BMD) showed enhanced gradients of risk for hip and non-hip major osteoporotic fractures compared with TBS or the FRAX risk factors alone.

Co-author Professor John A Kanis, Emeritus Professor in Human Metabolism, University of Sheffield, stated, "The findings of this study support the use of TBS, not only as a standalone assessment of fracture risk but also, more importantly, as an independent contributor to a more global risk assessment that could permit its use alongside established risk assessment tools such as FRAX."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Top 10 Foods for Decreasing DHT Production and Preventing Hair Fall
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
Quiz on Low-Calorie Diet for Diabetes
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Fracture Fracture of Knee Cap Infantile Cortical Hyperostosis Colle’s Fracture Fracture Neck of Femur Amyotrophic Lateral Sclerosis (ALS) Screening for Osteoporosis Injuries Related to Sports Renal Osteodystrophy / Mineral Bone Disorder Scaphoid Fracture of The Wrist 

Most Popular on Medindia

How to Reduce School Bag Weight - Simple Tips Noscaphene (Noscapine) Nutam (400mg) (Piracetam) A-Z Drug Brands in India Blood Pressure Calculator Drug - Food Interactions Sinopril (2mg) (Lacidipine) Loram (2 mg) (Lorazepam) Iron Intake Calculator Diaphragmatic Hernia
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Trabecular Bone Score Can be A Standalone Predictor of Fracture Risk Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests