A research team led by an Indian origin scientist has uncovered the mechanism as to how aspirin prevents plaque build up in arteries.
Previous animal studies have shown that aspirin may protect against atherosclerosis.
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the leading cause of death in the United States. Other names for heart attack include acute myocardial infarction, coronary thrombosis, and coronary occlusion.
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To reach the conclusion, researcher Sampath Parthasarathy conducted the study using mouse model and cultured cells.
They found that aspirin -specifically its active byproduct salicylate- can greatly increase the expression of two proteins: paraoxonase 1 (PON1) and apolipoprotein A1 (ApoA1)
![Chest Pain]( "Chest Pain")
Ask any one who has experienced intense chest pain and they will vouch for the fact that it was the most frightening experience of their life!
However, low dose aspirin supplements could increase PON1 and ApoA1 levels by 7- and 12- fold, respectively.
Both of these proteins are beneficial components of the HDL complex, the "good cholesterol" that helps prevent atherosclerosis
ApoA1 removes bad cholesterol from the bloodstream while PON1 is an antioxidant that breaks down toxic lipid peroxides.
The study has been published online in the October issue of Journal of Lipid Research.
Source: ANI
RAS/SK
Chest Pain
Ask any one who has experienced intense chest pain and they will vouch for the fact that it was the most frightening experience of their life!
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However, low dose aspirin supplements could increase PON1 and ApoA1 levels by 7- and 12- fold, respectively.
Both of these proteins are beneficial components of the HDL complex, the "good cholesterol" that helps prevent atherosclerosis
ApoA1 removes bad cholesterol from the bloodstream while PON1 is an antioxidant that breaks down toxic lipid peroxides.
The study has been published online in the October issue of Journal of Lipid Research.
Source: ANI
RAS/SK
Angioplasty - Animation
Arteries supplying the heart is sometimes blocked by plaque leading to heart attack.Angioplasty is a method by which a part of the blocked artery is expanded to place a stent.Once this is done normal blood flow resumes and the heart regains its normal function.
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 Animation of heart attack symptoms - AnimationHeart attack can cause symptoms such as Chest pain or discomfort, Shortness of breath and pain in neck, back, arm, or shoulder and is due to blockage of blood supply to the heart muscles | Advertisement
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