Father`s Diet Affects the RNA of His Sperms, and Thus the Offspring
In two recent studies, researchers have found that a father's diet affects the levels of specific small RNAs in his sperm, which in turn can affect offspring.
In two recent studies, researchers have found that a father's diet affects the levels of specific small RNAs in his sperm, which in turn can affect offspring.
‘The DNA fragmentation index (DFI) analysis thereby makes it possible to personalise treatment and increase the chances of having children.’
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A new study, which is the largest study within this field of research so far, shows that DFI analysis can be used for selecting the most efficient treatment to involuntarily childless couples. The study is based on analyses of more than 1 600 such couples referred to the Reproductive Medicine Centre at Skåne University Hospital in Malmö, Sweden for help. All men who participated in the study underwent DFI analysis. Men with a high DNA fragmentation index (DFI) also have more chromosomal breaks, which is linked to lower fertility. The couples who participated in the study underwent assisted reproduction, either through the standard method in vitro fertilisation (IVF) or the more advanced - ICSI (intracytoplasmic sperm injection).
In standard IVF the harvested egg is mixed with a large number of sperms in a test tube. The goal is that the fertilisation will succeed without further measures or assistance. ICSI involves selecting a single viable sperm cell that is then injected into the egg through a needle.
UK Regulatory Probes Sperm Bank for Banning Dyslexic Donors
The largest Sperm Bank in Britain has banned people with neurological diseases to donate sperm for assisted reproductive technologies.
The largest Sperm Bank in Britain has banned people with neurological diseases to donate sperm for assisted reproductive technologies.
"In couples where the man had many chromosomal breaks, their best chance of becoming pregnant was to use ICSI rather than IVF. The DFI analysis thereby makes it possible to personalise treatment and increase the chances of having children", says Krzysztof Oleszczuk, PhD student at Lund University and senior consultant at Skåne University Hospital.
Spermine Inside Neurons Dampens the Neurons Excitability
One out of a 100 people suffer from epilepsy in which nerve cells lose their usual rhythm, and one out of 20 suffer a seizure at least once in their lifetime.
One out of a 100 people suffer from epilepsy in which nerve cells lose their usual rhythm, and one out of 20 suffer a seizure at least once in their lifetime.
To confirm these results, a follow-up multicentre study is currently underway, in which three hospitals in the greater Copenhagen area will participate within the scope of the EU funded research collaboration in the Öresund region on fertility - ReproUnion. However, Aleksander Giwercman is looking forward to immediately transferring this new knowledge into practice at the Reproductive Medicine Centre at Skåne University Hospital.
Size of the Female Reproductive Tract Influences the Evolution of Sperm
The sperm of rodents is at least twice as long as sperm of large mammals like primates, tigers, and even whales.
The sperm of rodents is at least twice as long as sperm of large mammals like primates, tigers, and even whales.
"Traditionally the main focus has been on the woman in cases where couples have difficulties to conceive. But our research and experience show that it is important to thoroughly study both partners", says Aleksander Giwercman. The study is published in the medical journal Andrology.
Source-Eurekalert
