A new study in CMAJ has found that structural muscle damage may be present in patients who have statin-associated muscle complaints. Statins are one of the most widely prescribed medications in the world, given their importance in reducing the risk of cardiovascular disease. Many patients on statins develop muscle weakness and pain. In some cases, muscle biopsies show underlying structural injury, even in patients without elevated levels of circulating creatine phosphokinase. The study, by researchers from the University of Bern, Switzerland and the Tufts-New England Medical Center in Boston, Massachusetts, looked at muscle biopsies from 83 patients, 20 of whom had never taken statins. They found significant muscle injury in patients who had taken statins, including several who had discontinued medication before the biopsy. "Although in clinical practice, the majority of patients with muscle symptoms improve rapidly after cessation of therapy, our findings support that a subgroup of patients appears to be more susceptible to statin-associated myotoxicity, suffering persistent structural injury," write Dr. Annette Draeger from the University of Bern and coauthors. They note there is a need to evaluate alternative treatment strategies for patients with significant muscle symptoms. Source: EurekalertRAS << Canada Witnesses 200 Percent Increase in Cardiovascular Med... Molecule Helps Breast Cancer Cells to Survive in the Bone M... >> Recommended Reading Cholesterol Cholesterol is produced by the body (liver) and is essential for normal body functioning. READ MORE Cholesterol - The Enigma Chemical The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is important for the normal metabolism of the body and is dangerous only if present in excess. READ MORE Low Cholesterol Diet - PUFA & MUFA Cholesterol - The Pivotal Chemical in Low Cholesterol Diet READ MORE Natural Remedies for Cholesterol – How Effective Are They? Certain natural remedies are effective in controlling high cholesterol, when aided by lifestyle changes. READ MORE Statins Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms but also offering several health benefits. READ MORE Most Popular on Medindia Daily Calorie Requirements Turmeric Powder - Health Benefits, Uses & Side Effects Drug Side Effects Calculator More News on: CholesterolCholesterol - The Enigma ChemicalStatinsNatural Remedies for Cholesterol – How Effective Are They?