About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Smoking Increases Atherosclerosis Risk

by VR Sreeraman on September 12, 2007 at 6:14 PM
Font : A-A+

Smoking Increases Atherosclerosis Risk

A new study has added to the list of health problems posed by smoking, by finding that it also contributes to atherosclerosis, or hardening of the arteries.

Researchers from Weill Cornell Medical College in New York City pinpoint their evidence to the addictive chemical in cigarettes - nicotine.

Advertisement

By comparing reduced-nicotine cigarettes like Quest 3 and Eclipse with regular cigarettes, researchers discovered that the degree of cigarette-smoke induced atherosclerosis in mice correlated with the levels of nicotine -- the higher the nicotine, the more disease.

"Right now, the general consensus is that the problem with cigarettes is tar and that nicotine is safe. That's why you can buy nicotine gum or patches to help you stop smoking. Our study presents new evidence that nicotine may not be safe at all, especially for your heart," says Dr. Daniel F. Catanzaro, principal investigator of the study.
Advertisement

The new study looked at two so-called "potentially reduced exposure products" (PREPs) -- Eclipse and Quest.

The study found that mice exposed to smoke from low-nicotine cigarettes had significantly smaller atherosclerotic lesions, compared to those exposed to regular cigarettes but still larger than lesions in control mice not exposed to cigarette smoke, which showed the least evidence of atherosclerosis.

"While our study seems to suggest that low-nicotine cigarettes are safer, we also know that smokers adjust their smoking habits to maintain their level of nicotine. In other words, if you switch to a low-nicotine product, you will probably increase the number of cigarettes you smoke, or change the way you smoke to get more nicotine out of each cigarette. The best thing to do is quit," says Dr. Catanzaro.

Researchers also found that iPF2alphaV, a marker for oxidative stress that has been linked with atherosclerosis in humans, increased proportionately with the level of nicotine. This finding may signify that nicotine promotes atherosclerosis, partially, by blocking production of nitric oxide, a chemical that mediates the protective functions of the lining of blood vessels.

"These findings are preliminary. Going forward we will want to look at whether doping cigarettes with extra nicotine increases their atherogenic potential; whether blockers of nicotine reduce atherosclerosis; and if oral administration of nicotine has the same effects," says Dr. Catanzaro.

The study is published in the journal Cardiovascular Toxicology.

Source: ANI
LIN/J
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Link between Dietary Intake of Plant-based Essential Fatty Acids and Death Risk
Aspirin may be Harmful When Used for Preventing 1st Heart Attack, Stroke
Pregnancy Complications Elevated Among Symptomatic COVID-19 Women
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cholesterol Health Hazards of Smoking Smoking And Cancer Smoking And Tobacco Heart Attack Diet Lifestyle and Heart Disease Bubbles and Brews - Alcohol Facts Cholesterol - The Enigma Chemical Smoking Cigarette Smoking - A Silent Killer 

Recommended Reading
Health Hazards of Smoking
Smoking causes many diseases and affects the overall health of smokers....
New Insights into Chronic Inflammation and Atherosclerosis
Rheumatoid arthritis, lupus, and other inflammatory rheumatic diseases are associated with a high .....
Second Hand Smoke Has Serious Consequence on a Child’s Heart
Finnish Research study has found that exposure even a small amount of smoke found in the ......
Bubbles and Brews - Alcohol Facts
There is more to alcohol than mere intoxication. Infamous because of its social abuse but indispensa...
Cholesterol
Cholesterol is produced by the body (liver) and is essential for normal body functioning....
Cholesterol - The Enigma Chemical
The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is im...
Cigarette Smoking - A Silent Killer
Smoking kills the smoker silently, pushing him towards serious illnesses, which slowly lead to ......
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the lead...
Smoking And Cancer
Smoking is the most important preventable cause of cancer in the world....
Smoking And Tobacco
Encyclopedia section of medindia briefs you about the History of Tobacco...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use