About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Scientists Identify Genetic Variants That may Help Predict Cancer Survival

by Rajashri on October 23, 2008 at 2:41 PM
Font : A-A+

 Scientists Identify Genetic Variants That may Help Predict Cancer Survival

Certain genetic variations that may help predict survival in cancer patients have been identified by researchers from University of Minnesota.

A research team led by Brian Van Ness, Ph.D, from Masonic Cancer Centre, University of Minnesota, claim to have identified combinations of genes associated with early clinical relapse of multiple myeloma, a cancer of the white blood cells that produce antibodies, which can help predict patient's response to treatment.

Advertisement

"Ultimately, the goal of this research is to predict drug efficacy and toxicity based on a patient's genetic profile, and develop individualized assessments and predictions for the right drug, at the right dose, for the right patient," said Van Ness.

"This approach offers the dual benefits of avoiding unnecessary treatment for patients less likely to respond to a particular drug, and targeting treatments to those who will benefit most," he added.
Advertisement

For the study, Van Ness and his colleagues analysed the genetic information that the International Myeloma Foundation has gathered from myeloma patients worldwide through its program, Bank On A Cure(r).

"Although myeloma is considered a fatal disease, individual patients have widely varied rates of disease progression and response to treatment because of attributes encoded in their DNA," said Van Ness.

According to Van Ness, the research study findings demonstrate that cancer outcomes differ because patients vary in the ways they absorb, distribute, metabolize, and transport drugs across cell membranes.

Individual variations in genes that regulate these biologic processes may not only affect the effectiveness of the drug, but also can result in adverse side effects.

The findings are reported in the current issue of the research journal BMC Medicine.

Source: ANI
RAS/SK
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Toothache
World AIDS Day 2021 - End Inequalities, End AIDS
Turmeric: Magic Ingredient to Keep you Healthy in Winter
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Genetics and Stem Cells Cancer Facts Cancer Christianson Syndrome Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Immune Checkpoint Inhibitors for Cancer Treatment Non-Communicable Diseases How Do Viruses Mutate and Why Does it Matter? 

Recommended Reading
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of ....
Biopsy-Introduction
Encyclopedia section of medindia explains in brief Introduction To Biopsy...
Liver Cancer - Animation
Liver is the largest organ inside the human body. It performs 500 different functions and processes ...
Christianson Syndrome
Christianson syndrome is a condition that occurs due to mutations (abnormal changes) in the gene SLC...
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Health Benefits of Dandelion Plant
What is dandelion? Dandelion greens are nutrition powerhouses with a wide range of health benefits. ...
How Do Viruses Mutate and Why Does it Matter?
Mutations are the sudden changes that occur in genetic materials. They occur as a part of evolution ...
Immune Checkpoint Inhibitors for Cancer Treatment
Immune checkpoint inhibitors are promising drugs to treat a variety of cancers and the FDA has appro...
Non-Communicable Diseases
Non-Communicable Diseases (NCDs) are a group of chronic non-infectious diseases which include Cardio...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use