Abnormal development of the cardiovascular system in people born premature might be the risk of heart failure but the actual cause remains unknown.

‘Children born before the 28th week are 17 times more likely to suffer heart failure than those born at full term.’

In recent years, scientists have become all the more interested in the consequences of preterm birth on, amongst other things, cardiovascular health in young adults. 




Complementing previous studies indicating a higher risk of hypertension, stroke and fatal cardiovascular disease, researchers at Karolinska Institutet have now uncovered a hitherto unknown connection between preterm birth and heart failure in a registry study of 2.6 million individuals born between 1987 and 2012.
"We found that the risk of heart failure was higher for individuals born preterm, and inversely correlated with duration of pregnancy, in that the earlier you're born, the greater the risk," explains lead author Hanna Carr, doctoral student at Karolinska Institutet's Department of Medicine in Solna.
The study shows that children born before the 28th week are 17 times more likely to suffer heart failure than those born at full term.
Individuals born a little later - in weeks 28 to 31 - ran just over three times the risk. This correlation held when children with birth defects were excluded from the analysis and other possible determinants, such as birth weight, socioeconomic situation and parental heart conditions, were controlled for.
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"It could be the case that the higher risk of heart failure remains when they grow older, in which case more people will be affected as heart failure is much more common in older people," says associate professor Anna-Karin Edstedt Bonamy, paediatrician, who led the project.
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Source-Eurekalert