While CT scans may lead to a small increase in risk of cancer among children and adolescents, University of Melbourne's Professor John Mathews said that this risk should be weighed against the large number of benefits provided by such scans in diagnosing and monitoring diseases.
The study findings are reported in the British Medical Journal today and involved researchers at eight other centres in Australia, Oxford University, and the International Agency for Research on Cancer in Lyon, France.
Professor Mathews said: "CT scans were very useful in providing detailed three dimensional pictures to diagnose or exclude disease in internal organs and in most cases, the benefits of having a scan clearly outweigh the risk of a later cancer. Nevertheless, our new findings will remind doctors to order CT scans only when there is a definite medical reason, and to insist that CT scans use the lowest possible X-ray dose'. he said."
It is well known that large doses of radiation can damage DNA and increase the risk of a later cancer. However, the radiation doses from CT scans are very small, and there has been uncertainty about whether such small doses would cause cancer, and whether any small increase in risk could be measured reliably.
This study answered questions by linking de-identified Medicare records of CT exposures for the entire population of young Australians, aged 0-19 years between 1985 and 2005, to cancers diagnosed up to the end of 2007.
The risk of cancer increased with the number of CT scans, and the proportional increase in risk was greater for those exposed at younger ages. Nevertheless, as CT usage increased with age, the majority of cancers in this study followed exposures in the teenage years. Although this study did not directly assess the effects of CT exposures after the age of 19, the results suggest that cancer risk will increase following CT scans in adult life.
With improvements in CT technology, the average radiation dose per scan is expected to fall, although CT scan numbers have continued to increase in many countries.