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Research Sheds Light on Role of Immune System in Psoriasis

by Kathy Jones on Oct 18 2012 6:42 PM

 Research Sheds Light on Role of Immune System in Psoriasis
Around 2% of the world's population is affected by psoriasis, which is a chronic inflammatory skin disorder.
A group of inflammatory molecules known as interleukins activate an immune response that causes itchy skin, but it is unclear how the skin cells and immune cells communicate. In a study published in the Journal of Clinical Investigation, researchers led by Manfred Kopf at the Swiss Federal Institute of Technology in Zürich, Switzerland found that mice lacking interleukin-36 (IL-36) were protected from immune-mediated skin inflammation. These results indicate that IL-36 might be a useful therapeutic target in the treatment of psoriasis.



Source-Eurekalert


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