In a new study published online February 5 in the Journal of the National Cancer Institute, researchers report that high-coverage human papillomavirus (HPV) vaccinations among adolescents and young women may result in a rapid reduction of genital warts, cervical cell abnormalities, and diagnostic and therapeutic procedures. Some of these genital abnormalities are precursors of cervical, vulvar, and vaginal cancers.
This study was undertaken to determine if the administration of the HPV vaccine reduced the risk of cervical intraepithelial neoplasia (CIN), a precursor of cervical cancer; external anogenital and vaginal lesions (or external genital lesions) of any grade severity; Pap test abnormalities; and procedures such as colposcopy and definitive therapy or excision of lesions.
Cervical Cancer - Types, Causes, Symptoms, Diagnosis, Treatment, Complications & Prevention
Cancer cervix refers to cancerous growth in the cervix and usually occurs in the transition called squamo-columnar junction.
Cancer cervix refers to cancerous growth in the cervix and usually occurs in the transition called squamo-columnar junction.
In the group representing uninfected women, vaccination was up to 100% effective in reducing the risk of HPV16/18-related high-grade cervical, vulvar, and vaginal lesions and the risk of HPV6/11-related genital warts. In the group representing the general population, vaccination reduced the risk of any lesion, genital warts, Pap abnormalities, and definitive therapy, irrespective of HPV type. The reduction in risk was statistically significant.
"Our results provide strong evidence to suggest that the ongoing HPV vaccination programs in adolescent girls and young women will result within a few years in a notable reduction of genital warts, cervical cytological abnormalities, and diagnosticand therapeutic procedures related to precursor lesions in the cervix, vulva, and vagina," the authors write. "It is anticipated that these reductions will eventually translate into lower rates of cancer of the cervix, vulva, and vagina."
Study Proves That Girls Are Aware of HPV Vaccine's Benefits
Majority of girls and young women don't believe the HPV vaccine protects them against other sexually transmitted infections, according to a new study by University of Illinois at Chicago
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RAS
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Vaccination against the human papillomavirus (HPV) is not cost-effective in the Netherlands, according to a study published online July 1 in the Journal of the National Cancer Institute
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African Americans With Far Less HPV Infection Than Whites Have Worse Survival Rates
A groundbreaking study suggests that having the human papillomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck.
A groundbreaking study suggests that having the human papillomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck.
