About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Research Finds Cholesterol That Is Necessary For Brain Function

by Aruna on October 6, 2009 at 9:20 AM
Font : A-A+

Research Finds Cholesterol That Is Necessary For Brain Function

Researchers in Sweden have shown that a derivative of cholesterol is necessary for the formation of brain cells by conducting experiments on mice.

Professor Ernest Arenas, from the medical university Karolinska Institutet, says that the study's findings may prove helpful for scientists in cultivating dopamine-producing cells outside the body.

Advertisement

In a research article published in the journal Cell Stem Cell, Prof. Arenas notes that the formation of dopamine-producing neurons during brain development in mice is dependent on the activation of a specific receptor in the brain by an oxidised form of cholesterol called oxysterol.

The researcher writes that dopamine-producing nerve cells play an important part in many brain functions and processes, from motor skills to reward systems and dependency.
Advertisement

They are also the type of cell that dies in Parkinson's disease, Prof. Arenas adds.

The current study has also shown that embryonic stem cells, cultivated in the laboratory, form more dopamine-producing nerve cells if they are treated with oxidised cholesterol.

According to the study report, the same treatment also reduced the tendency of the stem cells to show uncontrolled growth.

"Oxysterol contributes to a safer and better cultivation of dopamine-producing cells, which is a great advancement since it increases the possibility of developing new treatments for Parkinson s disease," says Prof. Arenas.

The researchers hoped that it will one day be possible to replace dead cells in the brains of Parkinson's patients with transplanted cultivated dopamine-producing cells.

Such cells can also be used to test new Parkinson's drugs, they believe.

Source: ANI
ARU
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First-Ever Successful Pig-To-Human Kidney Transplantation
World Osteoporosis Day 2021 -
Spirituality and Mental Health
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cholesterol High Cholesterol Parkinsons Disease Parkinsons Disease Surgical Treatment Heart Attack Diet Lifestyle and Heart Disease Body Mass Index Cholesterol - The Enigma Chemical Liposuction Brain 

Recommended Reading
Cholesterol Blocks Electrical Currents That Generate Heartbeat: Study
A new study has found that cholesterol can affect the flow of the electrical currents that generate ...
Junk Food Cholesterol may Pose the Greatest Heart Disease Risk
Health freaks know that high levels of total cholesterol and LDL cholesterol can increase the ......
Body Mass Index
Body mass index (BMI) is a simple tool that is generally used to estimate the total amount of body f...
Cholesterol
Cholesterol is produced by the body (liver) and is essential for normal body functioning....
Cholesterol - The Enigma Chemical
The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is im...
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the lead...
High Cholesterol
High cholesterol level in blood are a risk for heart disease and stroke. They get deposited in the w...
Liposuction
Liposuction is a cosmetic procedure, which is used to suck out the excess or abnormal fat deposition...
Parkinsons Disease
Parkinson’s disease is a neurodegenerative disease caused by progressive dopamine brain cells loss. ...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use