Women who used oral contraceptives were more likely than those who did not take the pill to have
a buildup of plaque in their arteries, researchers told an American Heart Association meeting
'The main concern is if you have higher plaque levels that you might develop a clot on one of
these plaques and have a stroke or a myocardial infarction (heart attack) or sudden cardiac
death,' Dr. Ernst Rietzschel of Ghent University in Belgium, who led the research, told
'That's the main risk with having plaque, with having atherosclerosis.'
Rietzschel's team studied 1,301 women ages 35 to 55.
Of them, 81 percent had used the pill, for an average of 13 years. The researchers saw a rise of
20 to 30 percent in arterial plaque in two big arteries -- the carotid in the neck and the
femoral in the leg -- for each decade of use.
The researchers measured plaque levels using a technique called vascular echography.
In atherosclerosis, there is a hardening and narrowing of the arteries caused by the slow
buildup of plaque, made up of fat, cholesterol, calcium and other material, on the inside of
Rietzschel said he did not think the findings should trigger alarms about the safety of the
'Bottom line -- don't discontinue your pill suddenly. Don't panic. Don't call your gynecologist
tomorrow morning,' Rietzschel said.
Other steps can be taken to cut cardiovascular disease risk among these women, he said, like
eating a healthier diet, getting more exercise, not smoking and controlling cholesterol.
But he added, 'There are other ways of doing contraception. Oral contraception is not the only
Dr. Gordon Tomaselli, a Johns Hopkins University cardiologist and American Heart Association
official, said he was surprised by the findings.
'It's a bit eye-opening, I think,' Tomaselli said in an interview.
The introduction of 'The Pill' in the 1960s revolutionized birth control practices and was a
major cultural milestone. The pill uses hormones to suppress ovulation.
Rietzschel said it was possible the findings indicated that there could be an upswing in heart
disease among women who have taken the pill, considering that those who began in the 1960s were
now reaching a peak age for such illness.
'We might be at the foot of a wave. But the wave might be a small ripple,' Rietzschel said.