About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Now Gold can Be Used to Diagnose Cancer Too!

by VR Sreeraman on August 1, 2007 at 7:28 PM
Font : A-A+

Now Gold can Be Used to Diagnose Cancer Too!

In addition to giving people an elegant decor, gold may also become a precious tool for cancer diagnosis soon.

Purdue University researchers have created gold nanoparticles that are capable of identifying marker proteins on breast cancer cells.

Advertisement

Lead researcher Joseph Irudayaraj, an associate professor of agricultural and biological engineering, says that the method will be about three times cheaper than the current analogous technology called flow cytometry, and that it has the potential to provide many times the quantity and quality of data.

"We hope that this technology will soon play a critical role in early detection and monitoring of breast cancer. Our goal is to see it in commercial use in about four years," said Irudayaraj.
Advertisement

The gold nanoparticles are tiny rod-shaped gold particles, even smaller than viruses, which are equipped with antibodies designed to bind to a specific marker on cell surfaces. Researchers analyse these surface markers, proteins on a cell's exterior, because they can contain valuable information about what type of cell they belong to or in what state that cell may be.

"In cancer diagnosis, the ability to accurately detect certain key markers will be very helpful because certain types of cancers have specific surface markers," Irudayaraj said.

While flow cytometry requires hundred to thousands of cells to diagnose cancer, the gold nanoparticles require only a few cells, which is why it may be advantageous when dealing with scarce sample sizes, says the researcher.

Working in collaboration with postdoctoral researcher Chenxu Yu and Harikrishna Nakshatri, a researcher at the Indiana University School of Medicine, Irudayaraj showed that the gold nanoparticles bind to three different markers-two were used to calculate the invasiveness of the cancer cell, while one was used to calculate the degree to which the other markers were expressed, or present.

Irudayaraj believes that the gold nanoparticles will be able to detect as many as 15 different markers in the future, possibly opening the door for even more comprehensive tests.

He is now planning to further develop the technology, and is researching mechanical properties of the nanoparticles and the surface markers to which they bind so that such nanorods could be created as are capable of binding to more markers and to provide more information about these markers and what they reveal about the state of the cell.

The new invention has been reported online in the journal Analytical Chemistry.

Source: ANI
SRM/B
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Fermented Skin Care
Television Binge-Watching May Boost the Risk of Deadly Blood Clots
Western Diet may Augment the Risk of Autoimmune Diseases
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Cancer Facts Cancer Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Immune Checkpoint Inhibitors for Cancer Treatment Non-Communicable Diseases 
Recommended Reading
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Health Benefits of Dandelion Plant
What is dandelion? Dandelion greens are nutrition powerhouses with a wide range of health benefits. ...
Immune Checkpoint Inhibitors for Cancer Treatment
Immune checkpoint inhibitors are promising drugs to treat a variety of cancers and the FDA has appro...
Non-Communicable Diseases
Non-Communicable Diseases (NCDs) are a group of chronic non-infectious diseases which include Cardio...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
ASK A DOCTOR ONLINE
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)