Scientists in Beijing, China, have successfully developed a liver tissue which closely mimics the structure of the organ and could be useful in drug testing and transplants in patients suffering from liver failure. The microfluidics-based tissue that copies the liver's complex lobules, the organ's tiny structures was built from a liver and an aorta, the body's main artery. In the lab, the engineered tissue had a metabolic rate that was closer to real-life levels than other liver models, and it successfully simulated how a real liver would react to various drug combinations. ‘Chinese scientists have developed liver tissue which can be used for clinical applications and screening drugs for side effects and potentially harmful interactions.’ The liver plays a critical role in digesting food and detoxifying the toxins in our body. But due to a variety of factors, including viral infections, alcoholism and drug reactions, the organ can develop chronic or acute problems. Liver failure can be life-threatening and can require a transplant, a procedure that currently depends on human donors. Jinyi Wang and colleagues came up with the new approach to create a tissue rather than depending on organ donors. The researchers conclude their approach could lead to the development of functional liver tissue for clinical applications and screening drugs for side effects and potentially harmful interactions. Source: Medindia << Monsanto's Glyphosate Now Most Heavily Used Herbicide Novel Method Transfers Mother's Beneficial Vaginal Microbes ... >> Recommended Reading Fatty Liver Disease: A Growing Health Problem in India Non alcoholic fatty liver disease (NAFLD) is the leading cause of liver dysfunction worldwide and is a rapidly growing health problem in India. READ MORE Current Treatments for Liver Cancer Current Treatments for Liver Cancer (also known as hepatoma or hepatocellular carcinoma) can result in complete cure of the disease if it is detected early. READ MORE Alcoholic Liver Disease Encyclopedia section of medindia gives general information about Alcoholic Liver Disease. READ MORE Drug Toxicity Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a drug, reaction to a drug or drug abuse. READ MORE Hepatitis A Hepatitis A is the most benign of the hepatitis viruses and usually has no long term side effects. Hepatitis A vaccine is available that is 95% effective in preventing the disease. READ MORE Living Donor Liver Transplant: What Are the Risks? The risk of dying as a result of a living donor liver segment removal is between 0.2-2.0%. The risk of morbidity is anywhere between 1.3% (in highly experienced centers) to 60%. READ MORE Milk Thistle Milk Thistle is a resourceful natural plant which has many medicinal benefits. In herbal medication milk thistle is used in cases of liver diseases. READ MORE Wilson's Disease This is a rare inherited systemic disorder of copper metabolism, affecting the liver mainly before other organs. READ MORE Most Popular on Medindia Daily Calorie Requirements Color Blindness Calculator Selfie Addiction Calculator More News on: Drug ToxicityLiver BiopsyHepatitis ASignature Drug ToxicityLiverWilson's DiseaseMilk ThistleCurrent Treatments for Liver CancerFatty Liver Disease: A Growing Health Problem in IndiaLiving Donor Liver Transplant: What Are the Risks?