About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

New Peptide to Copy Mimick the Actions of Good Cholesterol

by Enozia Vakil on March 22, 2013 at 4:00 PM
Font : A-A+

 New Peptide to Copy Mimick the Actions of Good Cholesterol

A new peptide has been introduced by scientists that is assumed to mimick the actions of good cholesterol when consumed by successfully genetically engineered tomatoes.

Published in the April issue of the Journal of Lipid Research, the study found that mice that were fed these tomatoes in freeze-dried and ground form had less inflammation and plaque build-up in their arteries.

Advertisement

"This is one of the first examples of a peptide that acts like the main protein in good cholesterol and can be delivered by simply eating the plant," said senior author Alan M. Fogelman.

"There was no need to isolate or purify the peptide -- it was fully active after the plant was eaten," added Fogelman, executive chair of the department of medicine and director of the atherosclerosis research unit at the David Geffen School of Medicine at University of California, Los Angeles (UCLA).
Advertisement

After the tomatoes were eaten, the peptide surprisingly was found to be active in the small intestine but not in the blood, suggesting that targeting the small intestine may be a new strategy to prevent diet-induced atherosclerosis, the plaque-based disease of the arteries that can lead to heart attacks and strokes, reports Science Daily.

Specifically for the study, the team genetically engineered tomatoes to produce 6F, a small peptide that mimics the action of apoA-1, the chief protein in high-density lipoprotein (HDL or "good" cholesterol).

"It seems likely that the mechanism of action of the peptide-enhanced tomatoes involves altering lipid metabolism in the intestine, which positively impacts cholesterol," said co-author Srinavasa T. Reddy, professor of medicine and molecular and medical pharmacology at UCLA.

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
International Day of Persons with Disabilities 2021 - Fighting for Rights in the Post-COVID Era
Effect of Blood Group Type on COVID-19 Risk and Severity
Woman with Rare Spinal Cord Defect from Birth Sues Doctor
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cholesterol Heart Attack Diet Lifestyle and Heart Disease Cholesterol - The Enigma Chemical Liposuction Heart Attack- Lifestyle Risks Statins Low Saturated Fat and Low Cholesterol Diet Natural Remedies for Cholesterol – How Effective Are They? Fiber Up Your Meals 

Recommended Reading
Good Cholesterol from Genetically Engineered Tomatoes
Scientists from ULCA have revealed that genetically altered tomatoes, when consumed produce a ......
Trans Fats Can Be Deadly for Women With Heart Disease
Trans fats, found in many packaged foods, are deadly for women with heart disease, says a new ......
Cholesterol
Cholesterol is produced by the body (liver) and is essential for normal body functioning....
Cholesterol - The Enigma Chemical
The word 'Cholesterol' rings danger bells as soon as it is mentioned. This important chemical is im...
Fiber Up Your Meals
A high fiber diet and good water intake are essential for a stress free body. High-fiber foods preve...
Heart Attack
Heart attack is the death of the heart muscle due to loss of blood supply. Heart disease is the lead...
Heart Attack- Lifestyle risks
Heart attack is the death of the heart muscle due to loss of blood supply. Simple guidelines to avoi...
Liposuction
Liposuction is a cosmetic procedure, which is used to suck out the excess or abnormal fat deposition...
Low Saturated Fat and Low Cholesterol Diet
To avoid obesity we must consciously control the quantity and the quality of fat that we eat and our...
Natural Remedies for Cholesterol – How Effective Are They?
Certain natural remedies are effective in controlling high cholesterol, when aided by lifestyle chan...
Statins
Statins are new wonder drugs that are proving to be efficacious, not merely in relieving symptoms bu...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use