A new study has identified the missing gene in mice that enables them to stay thin despite overeating. The discovery is expected to help develop ways to tackle obesity and diabetes. The missing gene is actually an enzyme that is required to assimilate amino acids. However the absence leads to an amino acid called 'leucine' that burns up excess calories, enabling the mice to stay thin. Obesity results from an imbalance in the simple equation of energy input versus energy output, because excess fuel is turned into fat. Previous research has found that high-protein diets, or leucine supplements, lead to weight loss. To find out what happens when leucine is lastingly increased, Christopher Lynch of the Pennsylvania State University College of Medicine in Hershey and his team inactivated a gene that normally wipes out this amino acid from the blood. Lynch said that the genetically modified mice 'seemed more hungry than the other mice' and ate more, but still stayed lean. He added that the animals "went crazy" when the researchers changed their food pattern to lower the amount of leucine they could eat. "They were sitting next to their food, panting and eating," Nature quoted Lynch, as saying. The animals on this reduced-leucine diet were soaked in sweat as they ate more and more, but still didn't put on weight. Lynch suggest that the animals might be using the amount of leucine in their systems to determine how much they 'ought' to eat to reach their optimum weight. The study is published in Sept 5 issue of Cell Metabolism. Source: ANILIN/J << Illegal Sex- Givers and Takers To Be Punished Italy, the First Out of Tropics to Report of Chikungunya Out... >> Recommended Reading Daily Calorie Requirements Are you health conscious? If yes, go ahead to find out your approximate daily calorie requirement, which varies depending on the lifestyle and activities. This calculator indicates an approximate calorie requirement for a person having a normal ... READ MORE Health Experts Worried Over Growing Obesity Rates in US Two-thirds of US adults and some 25 million children are obese or overweight, and the fatness of the land is harming Americans' health and threatening US competitiveness, a report READ MORE Scientists Identified Obesity Control Switch Researchers at Dana-Farber Cancer Institute have identified a long-sought "master switch" in mice for the production of brown fat. READ MORE 13 Daily Habits that Damage the Brain The brain is probably the most important organ in our body and it deserves special care and attention to keep it active and functioning well. Here are thirteen daily habits, you must know that can cause damage to your brain. READ MORE Bite Counter - A Gadget that Helps Stop Overeating Just like a pedometer counts aerobic steps, the bite counter counts every bite taken. It rings an alarm on nearing the danger zone of overeating set by the person. READ MORE Chronic Dieting - Is it an Eating Disorder? Chronic dieting is associated with eating disorders that mainly include unhealthy eating practices such as severe calorie restriction in diet of men or women who on a regular basis follow fad diets mainly to reduce weight. READ MORE DNA Finger Printing DNA fingerprinting is a technique which helps forensic scientists and legal experts solve crimes, identity thefts, legal suits and terrorism cases. READ MORE Mindful Eating for Healthy Thanksgiving 2016 Enjoying a hearty thanksgiving meal with just a few changes in the food choices we make and portion size can help us keep away from overeating. READ MORE Overeating Equals To Overcheating Stuffing your tummy with unwanted extra calories can have a negative impact on the body. Overeating means frequent intake of food even when not hungry. READ MORE Sleep Eating Disorders Sleep-related eating disorders are abnormal eating behaviors that occur during night. Sleep related eating disorder is a part of parasomnias. READ MORE Weight Loss Program For Men Maintaining a food diary and keeping a track of what you eat is the best way to keep your weight under check. READ MORE Most Popular on Medindia Post-Nasal Drip Loram (2 mg) (Lorazepam) Blood Donation - Recipients More News on: DNA Finger PrintingSleep Eating DisordersWeight Loss Program For MenBite Counter - A Gadget that Helps Stop OvereatingMindful Eating for Healthy Thanksgiving 2016Overeating Equals To Overcheating13 Daily Habits that Damage the BrainChronic Dieting - Is it an Eating Disorder?