About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Large Burns can Trigger Multitude of Problems

by Medindia Content Team on August 23, 2007 at 3:17 PM
Font : A-A+

Large Burns can Trigger Multitude of Problems

It has been seen that large burns can trigger multitudes of problems like cardiac problems, enhanced inflammatory and hypermetabolic responses in patients. Treatment has to be focused on not the burn but also on these problems.

In case of the burn it results in immediate, dramatic inflammatory response. It can also cause depletion of essential proteins, reduced bone density and muscle strength, and can compromise the function of vital organs. Severe burn also causes increased mortality in burnt patients. The researchers are still trying to analyze the roles played by inflammation and hypermetabolism in burns.

Advertisement

Marc G. Jeschke from Shriners Hospitals for Children, Texas, USA and colleagues conducted a prospective clinical trial of 189 paediatric burned patients over nine years to see if burn size is associated with differences in inflammation, body composition, protein synthesis and organ function.

Burn injuries involving more than 80% of the total body surface cause marked and prolonged inflammation, increases in hypermetabolism, catabolism, cardiac dysfunction and subsequently higher incidences of infection, sepsis and death. These effects were burn size-dependent.
Advertisement

Another outstanding finding was that effect of burn size on cardiac dysfunction. Only large burns caused cardiac dysfunction which was shown by Pereira et al. as one of the major contributor to mortality, implying the importance of adequate cardiovascular support and treatment.

Patients with larger burns also had higher levels of pro-inflammatory cytokines, such as Tumor Necrosis Factor and Interleukin-8. The authors think these give the inflammatory response an added boost, enhancing catabolism and hypermetabolism.



Source: Eurekalert
BIN/J
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Burns 

Recommended Reading
Burns
Burn injuries have reached epidemic proportions in recent years. Burn accident statistics show that ...
Burns - First Aid and Emergency Treatment Guide
A quick and simple first aid guide on how to administer treatment for first degree and second ......

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use