Researchers at Oxford found hitherto unrecognized cells in the eye that could be a new target for the development of highly selective drugs to regulate sleep and wakefulness.
A team of researchers at Oxford University has found hitherto unrecognized cells in the eye that could be a brand new target for the development of highly selective drugs to regulate sleep and wakefulness.
Most of us feel sleepy in a dimly lit place and alert in a bright place. The biological mechanism behind this was unexplained till now. The answer seems to be that specialized cells in the retina detect light and send brightness information to those regions of the brain that regulate sleep and levels of arousal.
About Sleep Disorder
Sleep disorders can either be having difficulty in getting sleep or dozing off at inappropriate time.
Sleep disorders can either be having difficulty in getting sleep or dozing off at inappropriate time.
According to their study published in the journal Nature Neuroscience, the team has been able to track the sleep pathway to the brain, showing that the retinal ganglion cells directly activated two sleep-inducing centers there.
Professor Russell Foster, the lead researcher said, “By targeting the specific mechanism controlling the action of retinal ganglion cells, it may be possible in the future to develop sophisticated treatments to regulate the sleep-wake cycles.”
The researchers opine the study will pave the way to a new class of sleeping pills and stimulants that would have the same effect as bright light, or darkness, depending on how the drug is designed.
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Insomnia — Overview
Difficulty in initiating and maintaining sleep is known as insomnia. It is a symptom that occurs due to other disorders and can cause daytime sleepiness.
Difficulty in initiating and maintaining sleep is known as insomnia. It is a symptom that occurs due to other disorders and can cause daytime sleepiness.
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