Medindia
Advertisement

Indian Researcher Comes Up With Strategy to Combat Drug-Resistant Bacteria

by Bidita Debnath on November 13, 2013 at 6:28 PM
Font : A-A+

 Indian Researcher Comes Up With Strategy to Combat Drug-Resistant Bacteria

Rahul Kohli, an Indian origin scientist is among the winners of a GlaxoSmithKline (GSK) "academic drug hunter" competition, that will help fast track his lab's work in combating drug-resistant bacteria.

With this new partnership, Rahul Kohli, MD, PhD, an assistant professor in the division of Infectious Diseases and department of Biochemistry and Biophysics at the Perelman School of Medicine at the University of Pennsylvania, and his lab can ramp up their efforts to discover drugs that stop the evolution in its tracks.

Advertisement

Rather than taking the conventional approach of modifying existing antibiotics to overcome resistance, Kohli's lab aims to target the very pathways by which bacteria adapt to antibiotics and evolve resistance.

Kohli's team, spearheaded by Charlie Mo, a graduate student in Biochemistry and Molecular Biophysics, will now have access to 1.8 million compounds kept in GSK's chemical library and their other drug discovery technologies.
Advertisement

Kohli said that the search is on to find a molecule that can disrupt the pathway that allows bacteria to acquire drug resistance, asserting that the hope is that such a molecule can make bacteria more sensitive to existing antibiotics or slow the acquisition to the resistance, both of which would be valuable in the clinic.

This is GSK's first Discovery Fast Track competition in North America, which is designed to translate academic research into starting points for new potential medicines. There were eight winners in total across the country, selected from an initial pool of over 140 applications across 17 therapeutic areas and from 70 different institutions.

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
'Hybrid Immunity' may Help Elude COVID-19 Pandemic
Stroop Effect
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Shigellosis MRSA - The Super Bug Food Safety for Health Antibiotics 

Recommended Reading
New Delhi Multidrug Resistant Bacteria Found in Toronto Hospital
A hospital in Canada detected the presence of New Delhi Metallo-ß-lactamase-1-Producing Klebsiell...
Study Insists On Improved Approach To Fight Against Drug Resistant Bacteria
A new study has found that a small molecule composed of one atom of oxygen and one of nitrogen ......
Concern Over Use of Drugs in Animal Feed
Drugs fed to animals to promote growth may lead to the emergence of antibiotic resistant bacteria, ....
New Technique Helps Target Antibiotic-resistant Bacteria
Scientists have developed a novel method which targets antibiotic resistant bacteria and protects .....
Antibiotics
Antibiotics are among the most used and abused medications. This article explains some general featu...
MRSA - The Super Bug
MRSA infection is the most dreaded hospital or community acquired infection that can become ......
Shigellosis
Shigellosis or Bacillary Dysentery is a common cause of gastro-enteritis worldwide and can cause blo...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use