Verbal short-term memory was enhanced by tickling the brain with low-intensity electrical stimulation in a specific area, shows study by Mayo Clinic. The study published in Brain found word recall was enhanced with stimulation of the brain's lateral temporal cortex, the regions on the sides of the head by the temples and ears.
Patients recalled more words from a previously viewed list when low-amplitude electrical stimulation was delivered to the brain. One patient reported that it was easier to picture the words in his mind for remembering.
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‘Stimulating the brain's lateral temporal cortex with low-intensity electrical stimulation enhanced short term memory.’
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"The most exciting finding of this research is that our memory for language information can be improved by directly stimulating this underexplored brain area," says Michal Kucewicz, Ph.D., a Mayo Clinic researcher in the Department of Neurology and co-first author. Dr. Kucewicz compares the stimulation to "tickling" the brain.
Memory impairments are a prevalent, costly problem in many brain diseases. Medication and behavioral therapies have limited effectiveness in many cases. "While electrical stimulation of the brain is emerging as potential therapy for a wide range of neurological and psychiatric diseases, little is known about its effect on memory," says Gregory Worrell, M.D., Ph.D., a Mayo Clinic neurologist and senior author of the article.
![Constant Worrying Can Cause Short Term Memory Loss]( "Constant Worrying Can Cause Short Term Memory Loss")
Constantly stewing over a problem can lead to excessive release of cortisol in the brain which can cause short-term memory loss or mental disability, says a study.
The Mayo researchers are part of a multicenter collaboration led by Michael Kahana, Ph.D., University of Pennsylvania in Philadelphia. This collaboration includes seven academic medical centers.
"The next step for this project is to determine how to best apply electrical current in terms of the exact location within this area of the brain, timing and parameters of stimulation," says Brent Berry, M.D., Ph.D., a Mayo Clinic researcher in the Department of Physiology and Biomedical Engineering and co-first author.
In this study, Drs. Kucewicz and Berry, and colleagues focused their study on four areas of the brain known to support memory for facts and events that can be consciously recalled.
Study Overview
The memory testing was done with patients undergoing evaluation for surgery to address seizures. These patients agreed to have their memory investigated using the electrodes implanted in their brains for surgical evaluation. It is common for people with epilepsy to have memory problems because the brain circuits that underlie memory function often are affected by epilepsy. In the study, patients were instructed to read a list of words -- one at a time -- from a computer screen. Electrical stimulation was applied some of this time. Patients then attempted to freely recall the words in any order.
Among 22 patients, the researchers found enhanced memory performance in the four patients with stimulation of the lateral temporal cortex but not among those with the other brain regions stimulated.
"These findings may lead to new stimulation devices that treat deficits in memory and cognition," says Jamie Van Gompel, M.D., a Mayo Clinic neurosurgeon specializing in brain stimulation and an author in the study.
The authors note study limitations include pain and seizure medications that may affect patient performance, the hospital setting that may disrupt patients' sleep and wake cycles, and the fact that epilepsy affects memory.
Source: Eurekalert
Constant Worrying Can Cause Short Term Memory Loss
Constantly stewing over a problem can lead to excessive release of cortisol in the brain which can cause short-term memory loss or mental disability, says a study.
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The Mayo researchers are part of a multicenter collaboration led by Michael Kahana, Ph.D., University of Pennsylvania in Philadelphia. This collaboration includes seven academic medical centers.
"The next step for this project is to determine how to best apply electrical current in terms of the exact location within this area of the brain, timing and parameters of stimulation," says Brent Berry, M.D., Ph.D., a Mayo Clinic researcher in the Department of Physiology and Biomedical Engineering and co-first author.
In this study, Drs. Kucewicz and Berry, and colleagues focused their study on four areas of the brain known to support memory for facts and events that can be consciously recalled.
Study Overview
The memory testing was done with patients undergoing evaluation for surgery to address seizures. These patients agreed to have their memory investigated using the electrodes implanted in their brains for surgical evaluation. It is common for people with epilepsy to have memory problems because the brain circuits that underlie memory function often are affected by epilepsy. In the study, patients were instructed to read a list of words -- one at a time -- from a computer screen. Electrical stimulation was applied some of this time. Patients then attempted to freely recall the words in any order.
Among 22 patients, the researchers found enhanced memory performance in the four patients with stimulation of the lateral temporal cortex but not among those with the other brain regions stimulated.
"These findings may lead to new stimulation devices that treat deficits in memory and cognition," says Jamie Van Gompel, M.D., a Mayo Clinic neurosurgeon specializing in brain stimulation and an author in the study.
The authors note study limitations include pain and seizure medications that may affect patient performance, the hospital setting that may disrupt patients' sleep and wake cycles, and the fact that epilepsy affects memory.
Source: Eurekalert
How Do Short-term Memories Become Long-term Memories?
Most memories last for few seconds and some last a lifetime. Researchers found that the reason behind this could be related to the way we process sound.
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 By Age 25, Most of Us Have Made Important Memories: UNH ResearchMost important memories of their lives are made by people by the age of 25, suggests a new research from the University of New Hampshire. | Advertisement
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