About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Imatinib Resistance Could be Predicted

by Rathi Manohar on July 31, 2010 at 1:49 PM
Font : A-A+

Imatinib Resistance Could be Predicted

Patients with resistance to imatinib, the standard treatment for chronic myeloid leukemia (CML), could be identified through a new way, claim scientists in Japan.

Results are published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Advertisement

Imatinib, currently sold as Gleevec by Novartis, revolutionized the treatment of leukemia when it was approved in 2001. Yet imatinib comes with its own set of problems, chiefly resistance. Although resistance is relatively rare, occurring among 2 percent and 10 percent depending on the definition, it can cause unwanted problems both biologically and psychologically.

New drugs under development for the treatment of CML often tout their ability to overcome imatinib resistance, but determining who will develop resistance remains a challenge.
Advertisement

At the Hokkaido University Graduate School of Medicine, Yusuke Ohba, M.D., Ph.D., an associate professor, and colleagues tested the feasibility of a fluorescence resonance energy transfer biosensor in measuring the activity of leukemia cells.

"Using this test, we are now able to identify and predict the most suitable treatment option for individual chronic myeloid leukemia patients," said Ohba. "This technique is both sensitive and practical to use; it is especially useful for patients who are in relapse, a case in which the clinician's important decision regarding the next step in treatment must be made quickly and accurately."

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
World Heart Day 2021 -
Are Black Foods the New Superfood?
Ten Fruits for Diabetics
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.


Recommended Reading
Chronic Myeloid Leukemia
Chronic myeloid Leukemia is one of the most common types of blood cancer. It is characterized by .....
Clinical Trials
Clinical trials are experiments that yield useful information to clinicians if a particular ......
Quiz on Cancer
Cancer, is the second most leading cause of death worldwide. Cancer is not just one disease but ......
Leukemia / Blood Cancer
Leukemia is cancer of blood-forming tissues in the body....

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use